Protein Alignment Tsp42Eh and TSPAN1

DIOPT Version :9

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 52/240 - (21%)
• Similarity: 88/240 - (36%)
• Gaps: 51/240 - (21%)

  Fly     1 MYCTTRLLRYVLCVISGICALGGCLLIWYGAWL-LDSLS--------EEQRMLGMDHGEDLAAVL 56
            |.|.: .::.::.:.:.:..|.|..|:..|.|: :|..|        ....|..::.|..|.|.
Human     1 MQCFS-FIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAA- 63

  Fly    57 CVLLGTVIVVASIFGSVAVAKDSRVLLIC--YAVLLVFLLIVQIVLVSISYAA-SRDFLPDSLRQ 118
                |.|:......|......:|:..|:.  :.:||:|:..|...:|::.|.. :..||...:..
Human    64 ----GVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVP 124

  Fly   119 GLDDLWDLQHEGNSTLNTYEEWLHCCGRNSAEDYLHLEKMP--------PPSCC-------LNRD 168
            .:...:..|.:.....||..:.|.|||..:..|:   |..|        ||.||       .|..
Human   125 AIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDF---EDSPYFKENSAFPPFCCNDNVTNTANET 186

  Fly   169 CTKHL--NLFMTGCEVKFKEY----------VGAKTANFHSLSWF 201
            |||..  :..:.||   |.:.          ||...|....|.:|
Human   187 CTKQKAHDQKVEGC---FNQLLYDIRTNAVTVGGVAAGIGGLEFF 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspannin	8..220	CDD:278750	50/233 (21%)
		tetraspanin_LEL	109..192	CDD:239401	25/109 (23%)
TSPAN1	XP_011538762.1	Tetraspannin	7..214	CDD:278750	45/217 (21%)
		uroplakin_I_like_LEL	110..212	CDD:239409	24/107 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900