Protein Alignment Tsp42Eh and TSPAN1

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 240
• Identity: 52/240 - (21%)
• Similarity: 88/240 - (36%)
• Gaps: 51/240 - (21%)

  Fly     1 MYCTTRLLRYVLCVISGICALGGCLLIWYGAWL-LDSLS--------EEQRMLGMDHGEDLAAVL 56
            |.|.: .::.::.:.:.:..|.|..|:..|.|: :|..|        ....|..::.|..|.|.
Human     1 MQCFS-FIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAA- 63

  Fly    57 CVLLGTVIVVASIFGSVAVAKDSRVLLIC--YAVLLVFLLIVQIVLVSISYAA-SRDFLPDSLRQ 118
                |.|:......|......:|:..|:.  :.:||:|:..|...:|::.|.. :..||...:..
Human    64 ----GVVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVP 124

  Fly   119 GLDDLWDLQHEGNSTLNTYEEWLHCCGRNSAEDYLHLEKMP--------PPSCC-------LNRD 168
            .:...:..|.:.....||..:.|.|||..:..|:   |..|        ||.||       .|..
Human   125 AIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYTDF---EDSPYFKENSAFPPFCCNDNVTNTANET 186

  Fly   169 CTKHL--NLFMTGCEVKFKEY----------VGAKTANFHSLSWF 201
            |||..  :..:.||   |.:.          ||...|....|.:|
Human   187 CTKQKAHDQKVEGC---FNQLLYDIRTNAVTVGGVAAGIGGLEFF 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	50/233 (21%)
TSPAN1	XP_011538762.1	Tetraspanin	7..>151	CDD:459767	29/148 (20%)
		uroplakin_I_like_LEL	110..212	CDD:239409	24/107 (22%)