Protein Alignment Tsp42Eh and TSPAN2

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 60/244 - (24%)
• Similarity: 98/244 - (40%)
• Gaps: 53/244 - (21%)

  Fly     6 RLLRYVLCVISGICALGGCLLIWYGAWL-----LDSLSEEQRMLGMDHGEDLAAVLCVLL--GTV 63
            |.::|:|...:.:..|.|..:|.:|.|.     :..||.|.:     ..|.....|.||:  |.:
Human     9 RCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDK-----SPEYFYVGLYVLVGAGAL 68

  Fly    64 IVVASIFGSVAVAKDSRVLL----ICYAVLL-------VFLLI---VQIVLVSISY-AASRDFLP 113
            ::....||.....::|:.:|    .|..|:.       ||..|   |.|..|...| .|..|:|.
Human    69 MMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLK 133

  Fly   114 DSLRQGLDDLWDLQHEGNSTLNTYEEWLHCCGRNSAEDYLHLEKMPPPSCCLNRDCTKHLNLFMT 178
            |            :.:||.||.|:.....|||:.|:|   .::...|.....:::|...:...::
Human   134 D------------RGKGNGTLITFHSTFQCCGKESSE---QVQPTCPKELLGHKNCIDEIETIIS 183

  Fly   179 GCEVKFKEYVGAKTANFHSLSWFLVIFEFAGSVTTCYLVDSIRNHRDRI 227
               ||. :.:|........|:.|.:||    |:..|.   :|||.||.|
Human   184 ---VKL-QLIGIVGIGIAGLTIFGMIF----SMVLCC---AIRNSRDVI 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	53/230 (23%)
TSPAN2	NP_005716.2	Tetraspanin	11..212	CDD:459767	52/228 (23%)
		CD81_like_LEL	110..186	CDD:239404	22/93 (24%)