Protein Alignment Tsp42Eh and TSPAN3

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 47/235 - (20%)
• Similarity: 100/235 - (42%)
• Gaps: 48/235 - (20%)

  Fly    18 ICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGSVAVAKDSRVL 82
            :|.:|..:.|.|..:  |...|:...|       :.||:.:.:|.::.:..:.|..|..::||..
Human    27 LCYVGAYVFITYDDY--DHFFEDVYTL-------IPAVVIIAVGALLFIIGLIGCCATIRESRCG 82

  Fly    83 LICYAVLLVFLLIVQIVLVSISYAASRDFLPDSLRQGLDDLWDLQHEGN-----STLNTYEEWLH 142
            |..:.::|:.:.:.::|:|.:.| ..|..:.:.:.:.:..::...:..|     ..::..:..||
Human    83 LATFVIILLLVFVTEVVVVVLGY-VYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLH 146

  Fly   143 CCGRNSAEDYLHLE-------KMPPPSCCLNRDCTKHLN--------LFMTGCEV----KFKEYV 188
            |||.::..|:.:.:       :..|.|||  |:...:.|        |:..|||.    |.:|.:
Human   147 CCGIHNYSDWENTDWFKETKNQSVPLSCC--RETASNCNGSLAHPSDLYAEGCEALVVKKLQEIM 209

  Fly   189 GAKTANFHSLSWFLVIF---EFAGSVTTCYLVDSIRNHRD 225
                  .|.: |..:.|   :..|.:..|.::  .|..||
Human   210 ------MHVI-WAALAFAAIQLLGMLCACIVL--CRRSRD 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	44/225 (20%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	44/228 (19%)
		TM4SF8_like_LEL	104..210	CDD:239416	21/114 (18%)