Protein Alignment Tsp42Eh and TSPAN5

DIOPT Version :10

• Sequence 1: NP_523634.1
• Gene: Tsp42Eh / 35617
• FlyBaseID: FBgn0033129
• Length: 231
• Species: Drosophila melanogaster
• Sequence 2: NP_005714.2
• Gene: TSPAN5 / 10098
• HGNCID: 17753
• Length: 268
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 44/211 - (20%)
• Similarity: 90/211 - (42%)
• Gaps: 50/211 - (23%)

  Fly    17 GICALGGCLLIWYGAWLLDSLSEEQRMLGMDHGEDLAAVLCVLLGTVIVVASIFGSVAVAKDSRV 81
            ||..||..|..|....:|.::|....:.|.|     ...|.:::|.|:.:....|.:...:::..
Human    30 GITFLGIGLWAWNEKGVLSNISSITDLGGFD-----PVWLFLVVGGVMFILGFAGCIGALRENTF 89

  Fly    82 LLICYAVLLVFLLIVQIVLVSISYAASRDFLPDSL--------RQGLDDLWDLQHEGNSTLNTYE 138
            ||..::|.|..:..:::....::: ..:|::.|.|        |...||: |||    :.::..:
Human    90 LLKFFSVFLGIIFFLELTAGVLAF-VFKDWIKDQLYFFINNNIRAYRDDI-DLQ----NLIDFTQ 148

  Fly   139 EWLHCCGRNSAEDY-LHL-----------EKMPPP-SCC--------LNRDC----------TKH 172
            |:..|||...|:|: |::           |:...| |||        :|..|          .:.
Human   149 EYWQCCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQ 213

  Fly   173 LNLFMTGCEVKFKEYV 188
            :.::..||..:|::::
Human   214 IVIYTKGCVPQFEKWL 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eh	NP_523634.1	Tetraspanin	8..217	CDD:459767	44/211 (21%)
TSPAN5	NP_005714.2	Tetraspanin	15..258	CDD:459767	44/211 (21%)
		TM4SF9_like_LEL	113..233	CDD:239412	26/123 (21%)