Protein Alignment Tsp42Eg and CD151

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_004348.2
• Gene: CD151 / 977
• HGNCID: 1630
• Length: 253
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 49/244 - (20%)
• Similarity: 101/244 - (41%)
• Gaps: 46/244 - (18%)

  Fly     3 CSTNVLKGFALFWDIILALFGLVVIGLGV-HIIYKFEHFN--------TAAFVIIAVGVVVVLTA 58
            |.|..||.....::....|.||.|:.:|: .:..|.::.:        ..|::::..|.||::|.
Human    11 CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTVVMVTG 75

  Fly    59 LFGALGAARESSATSKVFVVILIVLVILE----VLAVGFLWVFQTSLLINVDKTFDKLWNDQPVP 119
            :.|.....:|.....:::.::|:::.:||    :||..:.....|.|..|:..|..|.::
Human    76 VLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTMTKRYH----- 135

  Fly   120 IKPGNQ---SQIASLERWLDCCGNVGPSDY--------------ILPPNSCYN-----GESDKLN 162
             :||::   |.:..|::...|||:....|:              ::|.:.|..     |:.|..:
Human   136 -QPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHAS 199

  Fly   163 ----LE-GCRQKFLDFIADRWTTFNLVSLVLLGVELICALLAYVLANSI 206
                :| ||..|...||.:.......|.:.:..|::...:....|..|:
Human   200 NIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRSL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	44/226 (19%)
		tetraspanin_LEL	95..176	CDD:239401	23/107 (21%)
CD151	NP_004348.2	Tetraspanin	16..246	CDD:459767	46/235 (20%)
		CD151_like_LEL	112..220	CDD:239408	23/113 (20%)