DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Eg and CD63

DIOPT Version :9

Sequence 1:NP_523633.1 Gene:Tsp42Eg / 35616 FlyBaseID:FBgn0033128 Length:218 Species:Drosophila melanogaster
Sequence 2:NP_001244318.1 Gene:CD63 / 967 HGNCID:1692 Length:238 Species:Homo sapiens


Alignment Length:238 Identity:61/238 - (25%)
Similarity:98/238 - (41%) Gaps:50/238 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 LFWDIILAL----FGLVVIGLGVHIIYKFEHFNTAA------FVIIAVGVVVVLTALFGALGAAR 67
            |.:.::||.    .||:.:|:|..::........|.      .|||||||.:.|.|..|..||.:
Human    13 LLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACK 77

  Fly    68 ESSATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDKTFDKLWNDQPVPIKPGNQSQIASLE 132
            |:......|.:.|.:::::||.|....:||:..::...:..|     .|.:...|.|....:.|:
Human    78 ENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNF-----RQQMENYPKNNHTASILD 137

  Fly   133 RW---LDCCGNVGPSDY-ILP-------PNSC---------YNGESDKLNLEGCRQKFLDFIADR 177
            |.   ..|||....:|: .:|       |:||         .|.....::.|||.:|.     ..
Human   138 RMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKI-----GG 197

  Fly   178 WTTFN--LVSLVLLG---VELICALLAYVLANSIVNRWRRSKY 215
            |...|  :|:...||   ||::..:.|..|..||     ||.|
Human   198 WLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSI-----RSGY 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EgNP_523633.1 Tetraspannin 17..202 CDD:395265 54/219 (25%)
tetraspanin_LEL 95..176 CDD:239401 21/100 (21%)
CD63NP_001244318.1 Tetraspannin 10..227 CDD:395265 55/223 (25%)
CD63_LEL 105..203 CDD:239419 22/107 (21%)
Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731 234..238 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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