Protein Alignment Tsp42Eg and CD53

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 56/220 - (25%)
• Similarity: 102/220 - (46%)
• Gaps: 41/220 - (18%)

  Fly     4 STNVLKGFALFWDIILALFGLVVIGLGVHIIYKFEHFN-----------TAAFVIIAVGVVVVLT 57
            |..:||....|::::..:.|..::|.|::::.   |.|           |...|.:.||.::::.
Human     5 SLKLLKYVLFFFNLLFWICGCCILGFGIYLLI---HNNFGVLFHNLPSLTLGNVFVIVGSIIMVV 66

  Fly    58 ALFGALGAARESSATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDK----TFDKLWNDQPV 118
            |..|.:|:.:|:......|.::|:::::.||.....|:|::..|...|.|    :..:..:|
Human    67 AFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSD--- 128

  Fly   119 PIKPGNQSQIA--SLERWLDCCGNVGPSDYIL-PPNSCYNGESDKLNLEGCRQKFLDFIADRWTT 180
                 |.::.|  |::.:|.|||..|.||:.. ||.||   .||: .:|||..|     |..|..
Human   129 -----NSTKAAWDSIQSFLQCCGINGTSDWTSGPPASC---PSDR-KVEGCYAK-----ARLWFH 179

  Fly   181 FNLVSLVLLGVELICALLAYVLANS 205
            .|   .:.:|:..||..:..||..|
Human   180 SN---FLYIGIITICVCVIEVLGMS 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	51/204 (25%)
		tetraspanin_LEL	95..176	CDD:239401	25/87 (29%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	55/216 (25%)
		CD53_like_LEL	104..186	CDD:239417	28/101 (28%)