Protein Alignment Tsp42Eg and CD37

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 67/282 - (23%)
• Similarity: 106/282 - (37%)
• Gaps: 89/282 - (31%)

  Fly     6 NVLKGFALFWDIILALFGLVVIGLGVHIIY---KFEHFNTAAFV-------IIAV-GVVVVLTAL 59
            :::|.|...:::...:.|.::...|:.|:.   .|..|...|||       ::|: |:..:..||
Human     9 SLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGIAL 73

  Fly    60 FGALGAARESSATSKVFVVILIVLVILEVLAVGFLWVFQ-----TSLLINVDKTFDKLWNDQPVP 119
            .|.:||.:|......::..:|::|...:: .:|.|...|     .||...|:||..|...
Human    74 LGCVGALKELRCLLGLYFGMLLLLFATQI-TLGILISTQRAQLERSLRDVVEKTIQKYGT----- 132

  Fly   120 IKPGNQSQIASLERW------LDCCGNVGPSDY----IL---------PPNSCYNGES------- 158
                |..:.|:.|.|      |.|||...|.|:    ||         .|.||||..:
Human   133 ----NPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTIL 193

  Fly   159 DKLNL-----------------------------EGCRQKFLDFIADRWTTFNLVSLV--LLGVE 192
            ||:.|                             |||.|..     .:|...||:|:|  .|||.
Human   194 DKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGL-----QKWLHNNLISIVGICLGVG 253

  Fly   193 LICALLAYVLANSIVNRWRRSK 214
            |: .:...||:..:..|..|.|
Human   254 LL-EMTVMVLSVQLQRRALRRK 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	62/259 (24%)
		tetraspanin_LEL	95..176	CDD:239401	31/140 (22%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	62/255 (24%)
		CD37_CD82_like_LEL	108..243	CDD:239413	33/148 (22%)