Protein Alignment Tsp42Eg and TSPAN18

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 49/261 - (18%)
• Similarity: 90/261 - (34%)
• Gaps: 74/261 - (28%)

  Fly     1 MACSTNVLKGFALFWDIILALFGLVVIGLGVHIIYKFEHFN----------TAAFVIIAVGVVVV 55
            ::|    :|.....::..:.|.|..::.:|:.::.....|.          |.|::::|:|.::.
Human    16 LSC----MKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLF 76

  Fly    56 LTALFGALGAARESSATSKVFVVILIVLVILEVLAVGFLWVFQTSLL--------------INVD 106
            |....|..||.||:......|.:.::::.:.|:.|....::|:.:|.              .|..
Human    77 LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNNDT 141

  Fly   107 KTFDKLWNDQPVPIKPGNQSQIASLERWLDCCGNVGPSDY------------------------- 146
            ..|...||.  |.|..|             |||..||.|:
Human   142 DVFSATWNS--VMITFG-------------CCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREP 191

  Fly   147 ------ILPPNSCYNGESDKLNLEGCRQKFLDFIADRWTTFNLVSLVLLGVELICALLAYVLANS 205
                  :|....|..|.|..||.:||....|:...........:::.:|.:||...:.|..|...
Human   192 QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLFRG 256

  Fly   206 I 206
            |
Human   257 I 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	46/241 (19%)
		tetraspanin_LEL	95..176	CDD:239401	24/125 (19%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	47/249 (19%)
		uroplakin_I_like_LEL	115..228	CDD:239409	24/127 (19%)