Protein Alignment Tsp42Eg and TSPAN4

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_001426622.1
• Gene: TSPAN4 / 7106
• HGNCID: 11859
• Length: 330
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 50/219 - (22%)
• Similarity: 83/219 - (37%)
• Gaps: 48/219 - (21%)

  Fly    13 LFWDIILALFGLVVIGLGVHIIYKFEHFNT---------AAFVIIAVGVVVVLTALFGALGAARE 68
            |||     |.|..|:|:|:.:......|.|         ||.::|..|..|:.....|.|||.:|
Human   111 LFW-----LGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGFVGCLGAIKE 170

  Fly    69 SSATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDKTFDKLWNDQPVPIKP-----GNQSQI 128
            :......|.::|:::.:||. .:..|:...|          ||:.......:|.     |.|..:
Human   171 NKCLLLTFFLLLLLVFLLEA-TIAILFFAYT----------DKIDRYAQQDLKKGLHLYGTQGNV 224

  Fly   129 ASLERW------LDCCGNVGPSDYI-------LPPNSCYN-GESDKLNLEGCRQKFLDFIADR-W 178
            .....|      ..|||....:|:.       :|.:.|.. .||..|:..|...|...:...: |
Human   225 GLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAPGTWWKAPCYETVKVW 289

  Fly   179 TTFNLVSLVLLGVELICALLAYVL 202
            ...||:::.:.|   :|..|..:|
Human   290 LQENLLAVGIFG---LCTALVQIL 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	47/215 (22%)
		tetraspanin_LEL	95..176	CDD:239401	18/99 (18%)
TSPAN4	NP_001426622.1	None