Protein Alignment Tsp42Eg and TSPAN6

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 59/242 - (24%)
• Similarity: 105/242 - (43%)
• Gaps: 50/242 - (20%)

  Fly     1 MACSTNVLKGFALFWDIILALFGLVVIGLGVHIIYKFEHF--------NTAAFVIIAVGVVVVLT 57
            :.|..:||    |.:..|..:.|::::.:|:......|::        ....||:||.|.|::|.
Human    14 ITCFKSVL----LIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILL 74

  Fly    58 ALFGALGAARESSATSKVFVVILIVLVILEVLA--VGFLWVFQTSLLINVDKTFDKLWNDQPVPI 120
            ..||.....|.|:...|::.:.|.::.::|::|  |||  ||:..:..:....::|       .:
Human    75 GTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGF--VFRHEIKNSFKNNYEK-------AL 130

  Fly   121 KPGNQS------QIASLERWLDCCGNVGPSDYILP--------PNSCYNGE-------SDKLNLE 164
            |..|.:      .:..::..|.|||.....|:...        |.||...|       :||:|.|
Human   131 KQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNE 195

  Fly   165 GCRQKFLDFIADRWTTFNLVSLVLLGV---ELICALLAYVLANSIVN 208
            ||..|.:..|.   :...:|:.:..||   :||...|||.|:.:|.|
Human   196 GCFIKVMTIIE---SEMGVVAGISFGVACFQLIGIFLAYCLSRAITN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	53/220 (24%)
		tetraspanin_LEL	95..176	CDD:239401	22/101 (22%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	56/233 (24%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	23/108 (21%)