Protein Alignment Tsp42Eg and Tspan4

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_001390287.1
• Gene: Tspan4 / 64540
• MGIID: 1928097
• Length: 333
• Species: Mus musculus
• Alignment Length: 225
• Identity: 53/225 - (23%)
• Similarity: 84/225 - (37%)
• Gaps: 60/225 - (26%)

  Fly    13 LFWDIILALFGLVVIGLGVHIIYKFEHFNT---------AAFVIIAVGVVVVLTALFGALGAARE 68
            |||     |.|..|:|:|:.:.....:|.|         ||.::|..|..|:.....|.:||.:|
Mouse   114 LFW-----LGGCGVLGVGIWLAATQGNFATLSSSFPSLSAANLLIVTGTFVMAIGFVGCIGALKE 173

  Fly    69 SSATSKVFVVILIVLVILE-VLAVGFLWVFQTSLLINVDKTFDKLWNDQPVPIKP-----GNQSQ 127
            :......|.|:|:::.:|| .:||.|   |..|         ||:.:.....:|.     |.|..
Mouse   174 NKCLLLTFFVLLLLVFLLEATIAVLF---FAYS---------DKIDSYAQQDLKKGLHLYGTQGN 226

  Fly   128 IASLERW------LDCCGNVGPSDYI------LPPNSCYNGESDKLNL--------EGCRQKFLD 172
            :.....|      ..|||....:|:.      ..|:||....||...|        ..|.:
Mouse   227 VGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSDSCGLHEPGTWWKSPCYE---- 287

  Fly   173 FIADRWTTFNLVSLVLLGVELICALLAYVL 202
             ....|...||:::.:.|   :|..|..:|
Mouse   288 -TVKAWLQENLLAVGIFG---LCTALVQIL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	50/221 (23%)
		tetraspanin_LEL	95..176	CDD:239401	19/105 (18%)
Tspan4	NP_001390287.1	Tetraspanin	104..323	CDD:459767	53/225 (24%)
		NET-5_like_LEL	200..297	CDD:239418	20/110 (18%)