Protein Alignment Tsp42Eg and ROM1

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_000318.2
• Gene: ROM1 / 6094
• HGNCID: 10254
• Length: 351
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 58/269 - (21%)
• Similarity: 91/269 - (33%)
• Gaps: 90/269 - (33%)

  Fly    13 LFWDIILALFGLVVIGLGVHIIYKFEHFNT-----AAFVI-----IAVGVVVVLTALFGALGAAR 67
            |.|  :|||.|.|::....|::.:..|..|     ..|.:     :|.|.|.:.|.|.| :||:|
Human    24 LSW--LLALAGGVILLCSGHLLVQLRHLGTFLAPSCQFPVLPQAALAAGAVALGTGLVG-VGASR 85

  Fly    68 ES--SATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDKTFDKL-----------WNDQPVP 119
            .|  :|....:..:|..|::......|.|.|....|.:.:..:.|:.           :.|..||
Human    86 ASLNAALYPPWRGVLGPLLVAGTAGGGGLLVVGLGLALALPGSLDEALEEGLVTALAHYKDTEVP 150

  Fly   120 IKPGNQSQIASLERWLDCCGNVGPSD----------YILP----------------------PNS 152
            .....:..:..|:....|||..|..|          |:.|                      |.|
Human   151 GHCQAKRLVDELQLRYHCCGRHGYKDWFGVQWVSSRYLDPGDRDVADRIQSNVEGLYLTDGVPFS 215

  Fly   153 CYNGESDK------------------------LNLEGCRQKFLDFIAD--------RWTTFNLVS 185
            |.|..|.:                        |..:||.:..|:.:.|        ...||.|.:
Human   216 CCNPHSPRPCLQNRLSDSYAHPLFDPRQPNQNLWAQGCHEVLLEHLQDLAGTLGSMLAVTFLLQA 280

  Fly   186 LVLLGVELI 194
            |||||:..:
Human   281 LVLLGLRYL 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	56/265 (21%)
		tetraspanin_LEL	95..176	CDD:239401	23/147 (16%)
ROM1	NP_000318.2	peripherin_like_LEL	126..265	CDD:239415	22/138 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..351