Protein Alignment Tsp42Eg and Tspan33

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_001102697.1
• Gene: Tspan33 / 500065
• RGDID: 1560915
• Length: 283
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 64/270 - (23%)
• Similarity: 111/270 - (41%)
• Gaps: 72/270 - (26%)

  Fly     7 VLKGFALFWDIILALFGLVVIGLGVHIIYKFEHFNTA--------AFVIIAVGVVVVLTALFGAL 63
            ::|....|::::..:..:|::.:||: ....:|...|        |.::|.|||::.|....|.:
  Rat    21 LVKYLLFFFNMLFWVISMVMVAVGVY-ARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGCI 84

  Fly    64 GAARESSATSKVFVVILIVLVILEVLAVGFL-WVFQTSLLINVDKTFDK---LWNDQPVPIKP-- 122
            |:.||:....:.|.:.|.::.:|: ||.|.| :||.       ||...|   :.|:..|..:.
  Rat    85 GSLRENICLLQTFSLCLTIVFLLQ-LAAGILGFVFS-------DKARGKVSEIINNAIVHYRDDL 141

  Fly   123 GNQSQIASLERWLDCCGNVGPSDY------------------------ILP-PNS------CYNG 156
            ..|:.|...::...|||.:...|:                        .|| ||.      |..|
  Rat   142 DLQNLIDFGQKKFSCCGGISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQAVINTMCGQG 206

  Fly   157 -------ESDK-LNLEGCRQKFLDFIADRWTTFNLVSL--VLLGV---ELICALLAYVLANSIVN 208
                   |:.| :...||..|.::     |...||..|  |.||:   :|:..||:.||.|.|.:
  Rat   207 MQALDYLEASKVIYTNGCIDKLVN-----WIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKD 266

  Fly   209 RWRRSKYYQK 218
            :.:...|.|:
  Rat   267 QIKLQLYNQQ 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	58/244 (24%)
		tetraspanin_LEL	95..176	CDD:239401	24/124 (19%)
Tspan33	NP_001102697.1	Tetraspanin	22..262	CDD:459767	60/253 (24%)
		penumbra_like_LEL	116..236	CDD:239411	25/131 (19%)