Protein Alignment Tsp42Eg and TSPAN11

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: XP_011518981.1
• Gene: TSPAN11 / 441631
• HGNCID: 30795
• Length: 302
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 48/222 - (21%)
• Similarity: 92/222 - (41%)
• Gaps: 56/222 - (25%)

  Fly    14 FWDIILALFGLVVIGLGVHIIYK---------FEHFNTAAFVIIAVGVVVVLTALFGALGAARES 69
            ||     :.|..|:.:|:..:.:         ...|..:|:::|..||:|::|...|......|.
Human    27 FW-----VGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGFLGFGAILWER 86

  Fly    70 SATSKVFVVILIVLVILEVLAVGFLWVF----QTSLLINVDKTFDKLWNDQPVPIKPGNQSQIAS 130
            ......:..:|:|:.::|::|.....|:    ...|..::::|..:.:.      :||.....||
Human    87 KGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYG------QPGATQITAS 145

  Fly   131 LERW---LDCCGNVGPSD-----YIL--------PPNSCYN------GE----SDKLNLE-GCRQ 168
            ::|.   ..|||:...:|     |||        .|:||..      |:    |:...:| ||..
Human   146 VDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAHPSNIYKVEGGCLT 210

  Fly   169 KFLDFIADRWTTFNLVSLVLLGVELIC 195
            |...|:||     :|:.:..:|:.:.|
Human   211 KLEQFLAD-----HLLLMGAVGIGVAC 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	46/219 (21%)
		tetraspanin_LEL	95..176	CDD:239401	25/111 (23%)
TSPAN11	XP_011518981.1	Tetraspanin	16..>158	CDD:459767	28/141 (20%)
		CD151_like_LEL	112..220	CDD:239408	27/118 (23%)