Protein Alignment Tsp42Eg and tsp-8

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_510445.1
• Gene: tsp-8 / 181567
• WormBaseID: WBGene00006634
• Length: 282
• Species: Caenorhabditis elegans
• Alignment Length: 276
• Identity: 52/276 - (18%)
• Similarity: 93/276 - (33%)
• Gaps: 77/276 - (27%)

  Fly     1 MACSTNVLKGFALFWDIILALFGLVVIGLGVHIIY----------KFEH---FNTAAFVIIAVGV 52
            |....|.|:.....::....|.|:||.|||:.:::          ...|   |....:.::..|.
 Worm     1 MGSCVNALRIVTFLFNFAFWLSGVVVFGLGIWLLFDPAASDFFALHSTHPGAFRYVGWFLVGAGA 65

  Fly    53 VVVLTALFGALGAARESSATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDKT--------- 108
            :::|...||.:||.:.:......|..|||:...||:.|...|:..|..:...|:.:
 Worm    66 IIILVGYFGCIGAWKMNQCALAFFCCILILAFFLELAAAVTLFHKQEHIKHYVESSMYDTIRNRY 130

  Fly   109 ---------FDKL-------------------WNDQPVPIKPGNQSQIASLERWL---------- 135
                     ||.:                   |:.:|......|:.....:|..:
 Worm   131 SSETAFKDAFDTVQEKFECCGVKTYTDWLSARWDAEPSTQLEVNEEDAGRIEHGIGAFGGNKGTG 195

  Fly   136 ------DCCGNVGPSDYILPPNSC--------YNGESDKLNLEGCRQKFLDFIADRWTTFNLVSL 186
                  .||...|...|   ||:|        .|..:..:|..||.....:.::...:....|.:
 Worm   196 YGRVPSSCCNEHGKLSY---PNNCGRSFSQAPLNTYAQFINTRGCADAVYESVSSSLSLIVGVCV 257

  Fly   187 VLLGVELICALLAYVL 202
            ||..|:|:..:|:..|
 Worm   258 VLCIVQLLGIVLSMTL 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	49/260 (19%)
		tetraspanin_LEL	95..176	CDD:239401	19/141 (13%)
tsp-8	NP_510445.1	Tetraspanin	8..>151	CDD:459767	28/142 (20%)
		tetraspanin_LEL	108..243	CDD:239401	19/137 (14%)