Protein Alignment Tsp42Eg and Cd63

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_031679.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Alignment Length: 236
• Identity: 62/236 - (26%)
• Similarity: 104/236 - (44%)
• Gaps: 46/236 - (19%)

  Fly    13 LFWDIILAL----FGLVVIGLGVHIIYK--FEHFNTAA----FVIIAVGVVVVLTALFGALGAAR 67
            |.:.::||.    .||:.||:.|.::.|  ..|..||.    .||||||..:.|.|..|..||.:
Mouse    13 LLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFLVAFVGCCGACK 77

  Fly    68 ESSATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDKTFDKLWNDQPVPIKPGNQSQIA-SL 131
            |:......|.:.|.:::::||......:||:..:....:|:|.:...:.   :|....:.|. .|
Mouse    78 ENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNY---LKDNKTATILDKL 139

  Fly   132 ERWLDCCGNVGPSDY---------ILPPNSCYN-----GESDK---LNLEGCRQKFLDFIADRWT 179
            ::..:|||....:|:         .:|.:.|.|     |...|   ::.:||    ::.|| .|.
Mouse   140 QKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIHTQGC----VETIA-IWL 199

  Fly   180 TFN--LVSLVLLG---VELICALLAYVLANSIVNRWRRSKY 215
            ..|  ||:...||   ||::..:.:..|..||     ||.|
Mouse   200 RKNILLVAAAALGIAFVEVLGIIFSCCLVKSI-----RSGY 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	56/219 (26%)
		tetraspanin_LEL	95..176	CDD:239401	19/98 (19%)
Cd63	NP_031679.1	Tetraspanin	10..229	CDD:459767	57/223 (26%)
		CD63_LEL	105..203	CDD:239419	21/105 (20%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		1/2 (50%)