Protein Alignment Tsp42Eg and TSPAN1

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: XP_011538762.1
• Gene: TSPAN1 / 10103
• HGNCID: 20657
• Length: 258
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 51/242 - (21%)
• Similarity: 88/242 - (36%)
• Gaps: 66/242 - (27%)

  Fly     1 MACSTNVLKGFALFWDIILALFGLVVIGLGVHI---------IY-----KFEHFNTAAFVIIAVG 51
            |.| .:.:|...:.:::::.|.|..::.:|:.:         |:     ....|....:.:||.|
Human     1 MQC-FSFIKTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAG 64

  Fly    52 VVVVLTALFGALGAARESSATSKVFVVILIVLVILEVLAVGFLWVFQT------SLLI------- 103
            |||......|..||..||......|..||:::.|.||.|.....|:.|      :||:
Human    65 VVVFALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKD 129

  Fly   104 -NVDKTFDKLWNDQPVPIKPGNQSQIASLERWLDCCGNVGPSDY----------ILPPNSCYNGE 157
             ...:.|.::||               :..:.|.|||....:|:          ..||..|.:..
Human   130 YGSQEDFTQVWN---------------TTMKGLKCCGFTNYTDFEDSPYFKENSAFPPFCCNDNV 179

  Fly   158 SDKLN------------LEGCRQKFLDFIADRWTTFNLVSLVLLGVE 192
            ::..|            :|||..:.|..|.....|...|:..:.|:|
Human   180 TNTANETCTKQKAHDQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLE 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	48/226 (21%)
		tetraspanin_LEL	95..176	CDD:239401	21/116 (18%)
TSPAN1	XP_011538762.1	Tetraspanin	7..>151	CDD:459767	33/158 (21%)
		uroplakin_I_like_LEL	110..212	CDD:239409	20/116 (17%)