Protein Alignment Tsp42Eg and TSPAN3

DIOPT Version :10

• Sequence 1: NP_523633.1
• Gene: Tsp42Eg / 35616
• FlyBaseID: FBgn0033128
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 243
• Identity: 63/243 - (25%)
• Similarity: 97/243 - (39%)
• Gaps: 63/243 - (25%)

  Fly    13 LFWDIILALFGLVVIGLGVHIIY-KFEHF------NTAAFVIIAVGVVVVLTALFGALGAARESS 70
            :||.   |...|..:|..|.|.| .::||      ...|.||||||.::.:..|.|.....|||.
Human    19 IFWG---AAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESR 80

  Fly    71 ATSKVFVVILIVLVILEVLAVGFLWVFQTSLLINVDKTFDKLWNDQPVPIKPGNQSQIAS----- 130
            .....||:||:::.:.||:.|...:|::..:...||::..|::...     .|.....||
Human    81 CGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTY-----NGTNPDAASRAIDY 140

  Fly   131 LERWLDCCGNVGPSDY------------ILPPNSC------YNGE----SDKLNLEGCR------ 167
            ::|.|.|||....||:            .:|.:.|      .||.    || |..|||.
Human   141 VQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSD-LYAEGCEALVVKK 204

  Fly   168 -QKFLDFIADRWTTFNLVSLVLLGVELICALLAYVLANSIVNRWRRSK 214
             |:.:..:.  |......::.|||:...|.:|.           |||:
Human   205 LQEIMMHVI--WAALAFAAIQLLGMLCACIVLC-----------RRSR 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Eg	NP_523633.1	Tetraspanin	17..204	CDD:459767	58/227 (26%)
		tetraspanin_LEL	95..176	CDD:239401	25/114 (22%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	59/226 (26%)
		TM4SF8_like_LEL	104..210	CDD:239416	25/111 (23%)