DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp42Ef and Tsp42Ei

DIOPT Version :9

Sequence 1:	NP_523632.2	Gene:	Tsp42Ef / 35615	FlyBaseID:	FBgn0033127	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001260756.1	Gene:	Tsp42Ei / 35618	FlyBaseID:	FBgn0033130	Length:	229	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	63/221 - (28%)
Similarity:	120/221 - (54%)	Gaps:	9/221 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SSVKLIVYALDVLCTLLALVLISFGIY--VAVSYNLNEIGQLTAYG-YVGLGAAALLVVLWGYLS 66
            ::||.::..|:.:.::|.|.||:|||:  ::.:.|...||:..|.| .:.||...|::.::|.|:
  Fly     6 TTVKHVLLLLNFVFSVLGLALIAFGIFFLISAAENAVSIGKNVAGGLIIALGVVILIIAIFGCLA 70

  Fly    67 AWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKT---VASNLANALEATWEEELNSPGAMSLY 128
            |..|.....:.::..:.|:|:||  :::|.::...|   ::.::....:..||.|.|..||:|.|
  Fly    71 AIHEAPVRLLIYVGAVVLLILAQ--LIFLGMSSHGTKDGISGSINEGFDRLWESERNQTGALSYY 133

  Fly   129 QNWFQCCGRGSPQDY-IVNERLPPETCFRNHDKSKPENLIHTGCRVEFENYWQHLTKIFNILALV 192
            ::|.||||..|.:|| |::..:|...|..:.....|..:..|||:..|..|......:|.|:..:
  Fly   134 ESWLQCCGVNSSEDYWIIHHGIPSSCCPESKCMDTPSRVFKTGCKAAFVKYLDDKLLVFKIVCWL 198

  Fly   193 LIGFELLLSVISCRLCNSIRNDARRS 218
            |:..|.:.:|....|.:|::|.:||:
  Fly   199 LVIGEAVGAVFGWLLYSSVKNQSRRN 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspannin	7..211	CDD:278750	59/210 (28%)
Tsp42Ef	NP_523632.2	tetraspanin_LEL	103..181	CDD:239401	25/78 (32%)
Tsp42Ei	NP_001260756.1	Tetraspannin	7..217	CDD:278750	59/211 (28%)
		DUF373	<17..>101	CDD:299895	24/85 (28%)
		tetraspanin_LEL	104..189	CDD:239401	26/84 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443027
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001737
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840