Protein Alignment Tsp42Ee and TSPAN14

DIOPT Version :10

• Sequence 1: NP_523631.1
• Gene: Tsp42Ee / 35614
• FlyBaseID: FBgn0029506
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_112189.2
• Gene: TSPAN14 / 81619
• HGNCID: 23303
• Length: 270
• Species: Homo sapiens
• Alignment Length: 92
• Identity: 23/92 - (25%)
• Similarity: 31/92 - (33%)
• Gaps: 28/92 - (30%)

  Fly   116 IFGEAKIEDLTQ------------QAQVAAAEKFKAPEAT----------------PAAGEASSS 152
            |...|||||.||            :..|.||...:|.|:.                |:..||...
Human    36 IIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLMKLVSDLKQFLILNDFPSVNEAIDQ 100

  Fly   153 TNVVTPIAEEDEEEVDDTGIDDKDIDL 179
            .|......:|:.:....|..|:..|||
Human   101 RNQQLRALQEECDRKLITLRDEVSIDL 127

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ee	NP_523631.1	Tetraspanin	8..217	CDD:459767	23/92 (25%)
TSPAN14	NP_112189.2	Tetraspanin	16..258	CDD:459767	23/92 (25%)
		TM4SF9_like_LEL	113..233	CDD:239412	5/15 (33%)
		Necessary and sufficient for interaction with ADAM10. /evidence=ECO:0000269|PubMed:26668317	114..232		5/14 (36%)