Protein Alignment Tsp42Ee and Cd63

DIOPT Version :10

• Sequence 1: NP_523631.1
• Gene: Tsp42Ee / 35614
• FlyBaseID: FBgn0029506
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_031679.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Alignment Length: 250
• Identity: 66/250 - (26%)
• Similarity: 124/250 - (49%)
• Gaps: 54/250 - (21%)

  Fly     4 GTSMVKYILFIF-----NTIVSVIGILGIVYGVLILKSIGVVEVNGQVGFPIQALMPIILISLGS 63
            |...||::|::.     ...|.:|.| |:...|::.::|......|       :|:|:::|::|:
Mouse     6 GMKCVKFLLYVLLLAFCACAVGLIAI-GVAVQVVLKQAITHETTAG-------SLLPVVIIAVGA 62

  Fly    64 IVVFISFLGCCGAIRESVCMTMSYATFLLILLILQLTFVVLLFTHREE--------FENAMGNVI 120
            .:..::|:|||||.:|:.|:.:::|.||.:::::::...:..:..|::        |:..|.|.:
Mouse    63 FLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYL 127

  Fly   121 ENAWNSEHTYKGGVFDTIQKSLHCCGSSSALDY-----IGKGDLVPPSCCSGSCLIPTNYYPGCR 180
            ::  |...|    :.|.:||..:|||:|:..|:     :.| |.||.|||       .|...||.
Mouse   128 KD--NKTAT----ILDKLQKENNCCGASNYTDWENIPGMAK-DRVPDSCC-------INITVGCG 178

  Fly   181 GKFVE--LMTTG---------SDNAKYVGIGLIGI---ELIGFIFACCLANNVRN 221
            ..|.|  :.|.|         ..|...|....:||   |::|.||:|||..::|:
Mouse   179 NDFKESTIHTQGCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ee	NP_523631.1	Tetraspanin	8..217	CDD:459767	64/240 (27%)
Cd63	NP_031679.1	Tetraspanin	10..229	CDD:459767	64/240 (27%)
		CD63_LEL	105..203	CDD:239419	28/111 (25%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		66/249 (27%)