Protein Alignment Tsp42Ee and UPK1A

DIOPT Version :10

• Sequence 1: NP_523631.1
• Gene: Tsp42Ee / 35614
• FlyBaseID: FBgn0029506
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: XP_054175633.1
• Gene: UPK1A / 11045
• HGNCID: 12577
• Length: 313
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 55/238 - (23%)
• Similarity: 100/238 - (42%)
• Gaps: 43/238 - (18%)

  Fly     4 GTSMVKYILFIFNTIVSVIGILGIVYGVLILKSIGVVEVNGQVGFPIQALMPIILISLGS-IVVF 67
            |:.:|..:|.:.|.|:.:.|:      .|..::|.|.....:| :|:..:.....:..|: |.:|
Human    13 GSPVVVGLLVVGNIIILLSGL------SLFAETIWVTADQYRV-YPLMGVSGKDDVFAGAWIAIF 70

  Fly    68 ISF-------LGCCGAIRESVCMTMSYATFLLILLILQLTFVVLLFTHREEFENAMGNVIEN--A 123
            ..|       .|...|:.....|.::|...:||:.|.:....:..:|||:...:....:.:.  .
Human    71 CGFSFFMVASFGVGAALCRRRSMVLTYLVLMLIVYIFECASCITSYTHRDYMVSNPSLITKQMLT 135

  Fly   124 WNSEHTYKG----GVFDTIQKSLHCCGSSSALDYI--------GKGDLV---PPSCC--SGSCLI 171
            :.|..|.:|    .::|.:.....|||:|..:|::        ...::|   ||.||  :|: .|
Human   136 FYSADTDQGQELTRLWDRVMIEQECCGTSGPMDWVNFTSAFRAATPEVVFPWPPLCCRRTGN-FI 199

  Fly   172 PTNYYPGCR-GKFVELMTTGSDNAKYVGIGL----IGIELIGF 209
            |.| ..||| |....|.|.|.  .:::|..:    .||...||
Human   200 PLN-EEGCRLGHMDYLFTKGC--FEHIGHAIDSYTWGISWFGF 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ee	NP_523631.1	Tetraspanin	8..217	CDD:459767	54/234 (23%)
UPK1A	XP_054175633.1	Tetraspanin	25..>163	CDD:459767	28/144 (19%)
		uroplakin_I_like_LEL	113..231	CDD:239409	29/121 (24%)