Protein Alignment Tsp42Ee and TSPAN2

DIOPT Version :9

• Sequence 1: NP_001260753.1
• Gene: Tsp42Ee / 35614
• FlyBaseID: FBgn0029506
• Length: 228
• Species: Drosophila melanogaster
• Sequence 2: NP_005716.2
• Gene: TSPAN2 / 10100
• HGNCID: 20659
• Length: 221
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 57/227 - (25%)
• Similarity: 102/227 - (44%)
• Gaps: 23/227 - (10%)

  Fly     4 GTSMVKYILFIFNTIVSVIGILGIVYGVLILKSIGVVEVNGQVGFPIQALMPI-ILISLGSIVVF 67
            |...:||:|..||.:..:.|...|.:|:.......:.|::.:...|....:.: :|:..|::::.
Human     7 GLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMA 71

  Fly    68 ISFLGCCGAIRESVCMTMSYATFLLILLILQLTFVVLLFTHREEFENAMGNVIENAWNSEHTYKG 132
            :.|.|||||:|||.|:..|:.|.||::...::|..|..|..:......:..:.|.|:|.....:|
Human    72 VGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDRG 136

  Fly   133 ---GVFDTIQKSLHCCGSSSALDYIGKGDLVPPSCCSGSCLIPTNY--YPGCRGKFVELMTTGSD 192
               |...|...:..|||..|:       :.|.|:|       |...  :..|..:...:::....
Human   137 KGNGTLITFHSTFQCCGKESS-------EQVQPTC-------PKELLGHKNCIDEIETIISVKLQ 187

  Fly   193 NAKYVGIGLIGIELIGFIFA---CCLANNVRN 221
            ....||||:.|:.:.|.||:   ||...|.|:
Human   188 LIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRD 219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ee	NP_001260753.1	Tetraspannin	8..219	CDD:278750	54/219 (25%)
		tetraspanin_LEL	106..187	CDD:239401	16/85 (19%)
TSPAN2	NP_005716.2	Tetraspannin	11..210	CDD:395265	52/212 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910