DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ed and CD53

DIOPT Version :9

Sequence 1:NP_001286152.1 Gene:Tsp42Ed / 35613 FlyBaseID:FBgn0029507 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_000551.1 Gene:CD53 / 963 HGNCID:1686 Length:219 Species:Homo sapiens


Alignment Length:211 Identity:59/211 - (27%)
Similarity:111/211 - (52%) Gaps:17/211 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VKYVLFIFNILFVICGILLITFGSIMVSTIKDFSGVGETFTANSVAIIILVLGCVVFLVAFMGCC 72
            :|||||.||:||.|||..::.|| |.:....:|..:.....:.::..:.:::|.::.:|||:||.
Human     9 LKYVLFFFNLLFWICGCCILGFG-IYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFLGCM 72

  Fly    73 GAIRENSCALTSYSVVMLVLLVSQ--LALIIYVWVDHVQ--IQQSLEKIVQTIWDQRKTDALLMD 133
            |:|:||.|.|.|:.:::|::|:::  ||::::|:...:.  :.:.|...:........|.| ..|
Human    73 GSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKA-AWD 136

  Fly   134 TLQRSFKCCGLNGFADYGITYPASCCDSPSNGTCALTQVMTRSSCLKAVDSFWDTNVSIIKYAGL 198
            ::|...:|||:||.:|:....||||   ||:...        ..|......::.:|...|....:
Human   137 SIQSFLQCCGINGTSDWTSGPPASC---PSDRKV--------EGCYAKARLWFHSNFLYIGIITI 190

  Fly   199 GVTAVELVAFIFACCL 214
            .|..:|::...||..|
Human   191 CVCVIEVLGMSFALTL 206

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EdNP_001286152.1 Tetraspannin 8..217 CDD:278750 59/211 (28%)
tetraspanin_LEL 104..189 CDD:239401 18/86 (21%)
CD53NP_000551.1 Tetraspannin 9..206 CDD:366035 58/209 (28%)
CD53_like_LEL 104..186 CDD:239417 20/93 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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