Protein Alignment Tsp42Ed and CD37

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 64/277 - (23%)
• Similarity: 108/277 - (38%)
• Gaps: 72/277 - (25%)

  Fly     8 VKYVLFIFNILFVICGILLITFGS-IMVSTIKDFSGVGETFTANSV-AIIILVLGCVVFLVAFMG 70
            :||.||:||:.|.:.|.|:..||. |::......|.||..|....: :.::.:.|.....:|.:|
Human    11 IKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGIALLG 75

  Fly    71 CCGAIRENSCALTSYSVVMLVLLVSQLALIIYVWVDHVQIQQSLEKIVQ-TI------------- 121
            |.||::|..|.|..|..::|:|..:|:.|.|.:.....|:::||..:|: ||
Human    76 CVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYGTNPEETAAE 140

  Fly   122 --WDQRKTDALLMDTLQRSFKCCG------------LNGFADYGITYPASCCD-SPSNGTCALTQ 171
              ||.          :|...:|||            |.|........|.||.: |.:|.:..|.:
Human   141 ESWDY----------VQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDK 195

  Fly   172 VMT----------------------------RSSCLKAVDSFWDTNVSIIKYAGLGVTAVELVAF 208
            |:.                            |..|.:.:..:...|:..|....|||..:|:...
Human   196 VILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICLGVGLLEMTVM 260

  Fly   209 IFACCLANQTRNSQRRQ 225
            :.:..|   .|.:.||:
Human   261 VLSVQL---QRRALRRK 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	61/266 (23%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	53/249 (21%)
		CD37_CD82_like_LEL	108..243	CDD:239413	24/144 (17%)