Protein Alignment Tsp42Ed and UPK1B

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 45/223 - (20%)
• Similarity: 85/223 - (38%)
• Gaps: 71/223 - (31%)

  Fly    12 LFIF-NILFVICGILL----ITFGS-------IMVSTIKDFSGVGETFTANSVAIIILVLGCVVF 64
            |.|| |::...|||.|    |.|.|       ::.:|..|     :.:.|..:.|.:   |..:|
Human    14 LLIFGNVIIGCCGIALTAECIFFVSDQHSLYPLLEATDND-----DIYGAAWIGIFV---GICLF 70

  Fly    65 LVAFMGCCGAIRENSCALTSYSVVMLVLLVSQLALIIYV------WVDHVQIQQSLEKI------ 117
            .::.:|..|.::.:...|.:|.::|.::...::|..|..      :..::.::|.||:.
Human    71 CLSVLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLKQMLERYQNNSPP 135

  Fly   118 ----------VQTIWDQRKTDALLMDTLQRSFKCCGLNGFADY--------------GITYPASC 158
                      |...||:    .:|.|      .|||:||.:|:              ...:|..|
Human   136 NNDDQWKNNGVTKTWDR----LMLQD------NCCGVNGPSDWQKYTSAFRTENNDADYPWPRQC 190

  Fly   159 CDSPSNGTCALTQVMTRSSCLKAVDSFW 186
            |...:     |.:.:...:|...|..|:
Human   191 CVMNN-----LKEPLNLEACKLGVPGFY 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	45/223 (20%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	33/164 (20%)
		uroplakin_I_like_LEL	118..230	CDD:239409	21/111 (19%)