Protein Alignment Tsp42Ed and TSPAN6

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 58/237 - (24%)
• Similarity: 105/237 - (44%)
• Gaps: 36/237 - (15%)

  Fly     9 KYVLFIFNILFVICGILLITFGSI-MVSTIKDFSGVGETFTANSVAIIILVLGCVVFLVAFMGCC 72
            |.||.|:..:|.|.|::|:..|.. .||....||.:.|  .|.:|..:::..|.|:.|:...||.
Human    18 KSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNE--KATNVPFVLIATGTVIILLGTFGCF 80

  Fly    73 GAIRENSCALTSYSVVM-LVLLVSQLALII-YVWVDHVQ--IQQSLEKIVQTIWDQRKTDALLMD 133
            ...|.::..|..|::.: ||.||..:|.|: :|:...::  .:.:.||.::.........:..:|
Human    81 ATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVD 145

  Fly   134 TLQRSFKCCGLNGFADYGIT-------YPASCC-----------DSPSNGTCALTQVMTRSSCLK 180
            .:|.:..|||:..:.|:..|       :|.|||           |..:|..|.: :|||
Human   146 KIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNEGCFI-KVMT------ 203

  Fly   181 AVDSFWDTNVSIIKYAGLGVTAVELVAFIFACCLANQTRNSQ 222
                ..::.:.::.....||...:|:....|.||:....|:|
Human   204 ----IIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	56/229 (24%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	56/229 (24%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	20/107 (19%)