Protein Alignment Tsp42Ed and TSPAN8

DIOPT Version :9

• Sequence 1: NP_001286152.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_001356689.1
• Gene: TSPAN8 / 7103
• HGNCID: 11855
• Length: 237
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 69/242 - (28%)
• Similarity: 123/242 - (50%)
• Gaps: 42/242 - (17%)

  Fly     8 VKYVLFIFNILFVICGILLITFGSIMVSTIKD---FSGVGETFTANSVAI-IILVLGCVVFLVAF 68
            :||.:|.||.||.:||||::.. :|.|....|   ..|..:..:::.||: |::.:|.::.::.|
Human     8 IKYSMFTFNFLFWLCGILILAL-AIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGF 71

  Fly    69 MGCCGAIRENSCALTSYSVVMLVLLVSQLALIIYVWVDHVQIQQSLEKIV-QTIWDQRK------ 126
            :||||||:|:.|.|..:.:.:|::|:.|:|..|...|    .:...::|| :|:::..|
Human    72 LGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAV----FKSKSDRIVNETLYENTKLLSATG 132

  Fly   127 ------TDALLMDTLQRSFKCCGL-NGFADYGIT---YPASC--------CDSPSNGTCALTQVM 173
                  .:|:::  .|..|||||| ||.||:|..   ||..|        |.| .||     :.:
Human   133 ESEKQFQEAIIV--FQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQRPCQS-YNG-----KQV 189

  Fly   174 TRSSCLKAVDSFWDTNVSIIKYAGLGVTAVELVAFIFACCLANQTRN 220
            .:.:|:..:..|...|:.|:.....|:..:|::..:|:..|..|..|
Human   190 YKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQIGN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_001286152.1	Tetraspannin	8..217	CDD:278750	67/237 (28%)
		tetraspanin_LEL	104..189	CDD:239401	27/109 (25%)
TSPAN8	NP_001356689.1	Tetraspannin	8..230	CDD:334016	66/234 (28%)
		TM4SF3_like_LEL	106..206	CDD:239407	27/111 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910