Protein Alignment Tsp42Ed and TSPAN16

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_036598.1
• Gene: TSPAN16 / 26526
• HGNCID: 30725
• Length: 245
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 49/230 - (21%)
• Similarity: 96/230 - (41%)
• Gaps: 44/230 - (19%)

  Fly     8 VKYVLFIFNILFVICGILLITF---GSIMVSTIKDFSGVGETFTANSVAIIILVLGCVVFLVAFM 69
            :|.:|.:.|....:.||:|:..   |....:::.:..|:...:..: |..:.||:||:..|:...
Human    11 LKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLGLSSAYLLH-VGNLCLVMGCITVLLGCA 74

  Fly    70 GCCGAIRENS-----CALTSYSVVMLVLLVSQLALIIYVWVDHVQIQQSLEKI------------ 117
            |..||.:|:.     |.|:...|:::.:..:.:.|:.:..|..|.::.:...:
Human    75 GWYGATKESRGTLLFCILSMVIVLIMEVTAATVVLLFFPIVGDVALEHTFVTLRKNYRGYNEPDD 139

  Fly   118 VQTIWDQRKTDALLMDTLQRSFKCCGLNGFADY---------GITYPASCCDSPSNGTC----AL 169
            ..|.|:      |:|:.|    ||||:|.:.|:         |.|||.|||.|..:.:|    ..
Human   140 YSTQWN------LVMEKL----KCCGVNNYTDFSGSSFEMTTGHTYPRSCCKSIGSVSCDGRDVS 194

  Fly   170 TQVMTRSSCLKAVDSFWDTNVSIIKYAGLGVTAVE 204
            ..|:.:..|...:.....|....:..:.||...::
Human   195 PNVIHQKGCFHKLLKITKTQSFTLSGSSLGAAVIQ 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	49/230 (21%)
TSPAN16	NP_036598.1	Tetraspanin	19..>155	CDD:459767	29/146 (20%)
		uroplakin_I_like_LEL	120..215	CDD:239409	23/104 (22%)