Protein Alignment Tsp42Ed and Prph2

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_037153.1
• Gene: Prph2 / 25534
• RGDID: 3549
• Length: 346
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 63/268 - (23%)
• Similarity: 102/268 - (38%)
• Gaps: 81/268 - (30%)

  Fly    12 LFIFNILFVICGILLITFGSIMVSTIKDFSGVGET----FTANSVAIIILVLGCVVFLVAFMGCC 72
            |::.|.|.|:.||:|.:.|..:...::..|.|.:.    |..||: |.:.||.||...:|...|.
  Rat    20 LWLMNWLSVLAGIVLFSLGLFLKIELRKRSDVMDNSESHFVPNSL-IGVGVLSCVFNSLAGKICY 83

  Fly    73 GAIRENSCA-----LTSYSVVMLV--LLVSQLALIIYVWVDHVQIQQSLEK-----IVQTIWDQR 125
            .|:.....|     |..|..|.:.  :::..:||..::      ::.|||.     :...:...|
  Rat    84 DALDPAKYAKWKPWLKLYLAVCVFFNVILFLVALCCFL------LRGSLESTLAYGLKNGMKYYR 142

  Fly   126 KTDA-------LLMDTLQRSFKCCGLNGFADY--------------------------------- 150
            .||.       ..:|.||..|||||.|||.|:
  Rat   143 DTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVD 207

  Fly   151 GITYPASCCDSPSNGTCALTQVMTRSSCLKAVD------SFW--DTNVSIIKY-----AGLGVTA 202
            |:  |.|||:..|...|...| :|.:|...:.|      :.|  ....:::.|     ..:||
  Rat   208 GV--PFSCCNPSSPRPCIQYQ-LTNNSAHYSYDHQTEELNLWLRGCRAALLNYYSSLMNSMGV-- 267

  Fly   203 VELVAFIF 210
            |.|:.::|
  Rat   268 VTLLIWLF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	63/268 (24%)
Prph2	NP_037153.1	Tetraspanin	16..181	CDD:459767	45/167 (27%)
		peripherin_like_LEL	120..262	CDD:239415	31/150 (21%)
		Interaction with MREG. /evidence=ECO:0000250	341..346