Protein Alignment Tsp42Ed and Tspan8

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_666122.1
• Gene: Tspan8 / 216350
• MGIID: 2384918
• Length: 235
• Species: Mus musculus
• Alignment Length: 222
• Identity: 63/222 - (28%)
• Similarity: 113/222 - (50%)
• Gaps: 16/222 - (7%)

  Fly     8 VKYVLFIFNILFVICGILLITFGSIMVSTIKDFSGV---GETFTANSVAI-IILVLGCVVFLVAF 68
            :||.:|.||.||.:||.|::.. :|.|...||...:   |::.|...:|: |::.:|.::.::.|
Mouse     8 LKYSMFFFNFLFWVCGTLILGL-AIWVRVSKDGKEIITSGDSSTNPFIAVNILIAVGSIIMVLGF 71

  Fly    69 MGCCGAIRENSCALTSYSVVMLVLLVSQLALIIYVWVDHVQIQQSLE-------KIVQTIWDQRK 126
            :|||||::|:.|.|..:.:.:|::|:.|:|..|.......:..:.|.       |::....|:.|
Mouse    72 LGCCGAVKESRCMLLLFFIGLLLILILQVAAGILGAAFKPEYNRILNETLYENAKLLSDNTDEAK 136

  Fly   127 TDALLMDTLQRSFKCCGL-NGFADYGITYPASCCDSPSNGT-CALTQ--VMTRSSCLKAVDSFWD 187
            .....|...|..|||||| ||.||:|..:..:.......|| ||..|  .:...:||..:...::
Mouse   137 DFQKAMIVFQSEFKCCGLENGAADWGNNFVEAKESCQCTGTDCATYQGSSVYPKTCLSLIKDLFE 201

  Fly   188 TNVSIIKYAGLGVTAVELVAFIFACCL 214
            .|:.|:.....|:..:|::..:|:..|
Mouse   202 KNIIIVIGIAFGLAVIEILGLVFSMVL 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	63/222 (28%)
Tspan8	NP_666122.1	Tetraspanin	8..230	CDD:459767	63/222 (28%)
		TM4SF3_like_LEL	106..204	CDD:239407	24/97 (25%)