DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tsp42Ed and tsp-13

DIOPT Version :9

Sequence 1:	NP_001286152.1	Gene:	Tsp42Ed / 35613	FlyBaseID:	FBgn0029507	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_741692.1	Gene:	tsp-13 / 189737	WormBaseID:	WBGene00006639	Length:	321	Species:	Caenorhabditis elegans

Alignment Length:	179	Identity:	59/179 - (32%)
Similarity:	90/179 - (50%)	Gaps:	24/179 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GVFVKYVLFIFNILFVICGILLITFGSIMVSTIKDF---------SGVGETF----TANSVAIII 56
            ||:.||.:|..||:|:|.|.||:..| :.:.|...|         ..|.|.|    |..:.:.||
Worm    54 GVWAKYGIFTANIVFLIVGGLLLAMG-VWLRTDSRFRNFISERYRQAVQEAFWEAPTLFAFSYII 117

  Fly    57 LVLGCVVFLVAFMGCCGAIRENSCALTSYSVVMLVLLVSQLALIIYVWVD----HVQIQQSLEKI 117
            :|||.|:.:||.:||||....:...|..||:|:.:|||:.|:..||:...    .|::..:|..:
Worm   118 IVLGAVMMVVAMLGCCGITGRSRPFLIIYSMVVFLLLVATLSCGIYLLYKKDGLDVELSDALNYM 182

  Fly   118 VQTIWDQRKTDALLMDTLQRSFKCCGLNGFADYGI---TYPASC---CD 160
            ||..:.........:|.||.:|:|||..|.:|:.:   ..|.||   ||
Worm   183 VQHYYQGPGVVQESLDHLQTAFRCCGNAGCSDFRVFRQDIPRSCDIRCD 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_001286152.1	Tetraspannin	8..217	CDD:278750	57/176 (32%)
Tsp42Ed	NP_001286152.1	tetraspanin_LEL	104..189	CDD:239401	18/67 (27%)
tsp-13	NP_741692.1	Tetraspannin	58..269	CDD:278750	57/175 (33%)
tsp-13	NP_741692.1	tetraspanin_LEL	165..242	CDD:239401	18/67 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16965
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840