Protein Alignment Tsp42Ed and tsp-14

DIOPT Version :10

• Sequence 1: NP_523630.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_001367834.1
• Gene: tsp-14 / 180761
• WormBaseID: WBGene00006640
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 302
• Identity: 69/302 - (22%)
• Similarity: 122/302 - (40%)
• Gaps: 106/302 - (35%)

  Fly     8 VKYVLFIFNILFVICGILLITFGSIMVSTIKDFSGVGETFTANSVAIIILVLGCVVFLVAFMGCC 72
            :|:::|:.|.:..:.|:.::..|..:.  ||||..|.......:.||:|.:.|..:.:|:|.|..
 Worm    54 LKWLVFLLNSIVFLVGVGILALGVYLF--IKDFREVKLVDIILNPAILISIFGFSICVVSFFGFM 116

  Fly    73 GAIREN--------SCALTSYSVVMLVLLV-------------SQLALIIYVWVDHVQIQQSLEK 116
            ||:|:|        :|...||.:|:.|.||             |...|::|. |.:....::|.:
 Worm   117 GALRDNIFLLKCFAACVFLSYILVVAVTLVFFTLFYTDTTEGLSANWLLLYA-VKNYHTNRNLAE 180

  Fly   117 IVQTIWDQRKTDALLMDTLQRSFKCCGLN----GFADYGITY----------------PASCCD- 160
            |              ||.||.:.:|||::    |:.|:.::|                |.|||.
 Worm   181 I--------------MDALQENLECCGVSSIAQGYRDWNMSYQFNCTNSNPQPEKCGVPFSCCRK 231

  Fly   161 ---SPSNGT------------C---ALTQ--------VMTRSSCLKAVDSFWDTNVSIIKYAGLG 199
               |.:.|:            |   |||:        :.|| .||:.:.:.::::.   .:.|..
 Worm   232 SVISEAAGSSNPLLPAMRSLECWQNALTKRPGDLEHDIYTR-GCLQPLRTLFESHA---VHVGAF 292

  Fly   200 VTAVELVAFIFACCLAN----------------QTRNSQRRQ 225
            | |:.:|....:.||.|                ..||.:||:
 Worm   293 V-ALLIVPVCISVCLTNILAKQVDHQRYLLEREARRNDRRRK 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_523630.1	Tetraspanin	8..216	CDD:459767	64/275 (23%)
tsp-14	NP_001367834.1	Tetraspanin	54..>193	CDD:459767	39/155 (25%)
		tetraspanin_LEL	145..286	CDD:351888	32/156 (21%)