Protein Alignment Tsp42Ed and Cd63

DIOPT Version :9

• Sequence 1: NP_001286152.1
• Gene: Tsp42Ed / 35613
• FlyBaseID: FBgn0029507
• Length: 227
• Species: Drosophila melanogaster
• Sequence 2: NP_001036045.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Alignment Length: 234
• Identity: 66/234 - (28%)
• Similarity: 125/234 - (53%)
• Gaps: 21/234 - (8%)

  Fly     1 MDCGGVFVKYVLFIFNILFVICGILLITFGSIMVSTIKDFSGVGETFTANSVAIIILVLGCVVFL 65
            |.|    ||::|::..:.|..|.:.||..| :.|..:...:...||...:.:.::|:.:|..:||
Mouse     7 MKC----VKFLLYVLLLAFCACAVGLIAIG-VAVQVVLKQAITHETTAGSLLPVVIIAVGAFLFL 66

  Fly    66 VAFMGCCGAIRENSCALTSYSVVMLVLLVSQLALII--YVWVDHV--QIQQSLEKIVQTIWDQRK 126
            |||:|||||.:||.|.:.::::.:.::::.::|:.|  ||:.|.|  :..:|.::.:|......|
Mouse    67 VAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNK 131

  Fly   127 TDALLMDTLQRSFKCCGLNGFADY----GIT---YPASCCDSPSNGTCA---LTQVMTRSSCLKA 181
            | |.::|.||:...|||.:.:.|:    |:.   .|.|||.:.:.| |.   ....:....|::.
Mouse   132 T-ATILDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVG-CGNDFKESTIHTQGCVET 194

  Fly   182 VDSFWDTNVSIIKYAGLGVTAVELVAFIFACCLANQTRN 220
            :..:...|:.::..|.||:..||::..||:|||....|:
Mouse   195 IAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ed	NP_001286152.1	Tetraspannin	8..217	CDD:278750	63/222 (28%)
		tetraspanin_LEL	104..189	CDD:239401	22/96 (23%)
Cd63	NP_001036045.1	Tetraspannin	10..227	CDD:395265	61/219 (28%)
		CD63_LEL	105..203	CDD:239419	24/99 (24%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		66/234 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810