DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ed and TSPAN3

DIOPT Version :9

Sequence 1:NP_001286152.1 Gene:Tsp42Ed / 35613 FlyBaseID:FBgn0029507 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_005715.1 Gene:TSPAN3 / 10099 HGNCID:17752 Length:253 Species:Homo sapiens


Alignment Length:240 Identity:58/240 - (24%)
Similarity:116/240 - (48%) Gaps:25/240 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 CGGVFVKYVLFIFNILFVICGILLITFGSIMVSTIKDFSGVGETFTANSVAIIILVLGCVVFLVA 67
            ||....|.||...|::|.....:|...|:.:..|..|:....|.......|::|:.:|.::|::.
Human     4 CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIG 68

  Fly    68 FMGCCGAIRENSCALTSYSVVMLVLLVSQLALIIYVWVDHVQIQQSLEKIVQTIWDQRKT----- 127
            .:|||..|||:.|.|.::.:::|::.|:::.:::..:|...:::..:::.:|.::   ||     
Human    69 LIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVY---KTYNGTN 130

  Fly   128 -DAL--LMDTLQRSFKCCGLNGFADYGIT----------YPASCC---DSPSNGTCALTQVMTRS 176
             ||.  .:|.:||...|||::.::|:..|          .|.|||   .|..||:.|....:...
Human   131 PDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAE 195

  Fly   177 SCLKAVDSFWDTNVSIIKYAGLGVTAVELVAFIFAC-CLANQTRN 220
            .|...|.......:..:.:|.|...|::|:..:.|| .|..::|:
Human   196 GCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EdNP_001286152.1 Tetraspannin 8..217 CDD:278750 55/230 (24%)
tetraspanin_LEL 104..189 CDD:239401 24/105 (23%)
TSPAN3NP_005715.1 Tetraspannin 9..232 CDD:395265 53/225 (24%)
TM4SF8_like_LEL 104..210 CDD:239416 24/108 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1406905at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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