Protein Alignment Tsp42Ec and CD63

DIOPT Version :9

• Sequence 1: NP_523629.1
• Gene: Tsp42Ec / 35612
• FlyBaseID: FBgn0033124
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_001244318.1
• Gene: CD63 / 967
• HGNCID: 1692
• Length: 238
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 52/238 - (21%)
• Similarity: 119/238 - (50%)
• Gaps: 26/238 - (10%)

  Fly     1 MGCLSGIVNFILYIVNIVF--LIVGILLIVLGSIMLSDLSRFDVAGSGTDPNTIPICVTVLGGLI 63
            |.|    |.|:||::.:.|  ..||::.:.:|:.::  ||:..:.|: |..:.:|:.:..:|..:
Human     7 MKC----VKFLLYVLLLAFCACAVGLIAVGVGAQLV--LSQTIIQGA-TPGSLLPVVIIAVGVFL 64

  Fly    64 FVVSFFGCYGIFRQSVCMTGAYTSMVFVLFILQLVLTCWVFVNRSAFLGDMSN-----LVNLLWD 123
            |:|:|.||.|..:::.|:...:...:.::.::::......:|.|...:.:.:|     :.|...:
Human    65 FLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKN 129

  Fly   124 SHDYTAMGVLEETFGCCGDTSYTNYNNI-GLS---VPGTCCGYLDRQATC----NTPSVYQSRPG 180
            :|..:.:..::..|.|||..:||::..| .:|   ||.:||  ::....|    |..:::  :.|
Human   130 NHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCC--INVTVGCGINFNEKAIH--KEG 190

  Fly   181 CSAKFEEFWNDNMDIIRWSGLGLCIFDLVVFLIAGALTNCMRS 223
            |..|...:...|:.::..:.||:...:::..:.|..|...:||
Human   191 CVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ec	NP_523629.1	Tetraspannin	7..221	CDD:278750	48/228 (21%)
		tetraspanin_LEL	104..193	CDD:239401	22/101 (22%)
CD63	NP_001244318.1	Tetraspannin	10..227	CDD:395265	47/223 (21%)
		CD63_LEL	105..203	CDD:239419	22/101 (22%)
		Lysosomal targeting motif. /evidence=ECO:0000250|UniProtKB:P41731	234..238		52/238 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3882
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810