Protein Alignment Tsp42Ec and CD53

DIOPT Version :10

• Sequence 1: NP_523629.1
• Gene: Tsp42Ec / 35612
• FlyBaseID: FBgn0033124
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 51/238 - (21%)
• Similarity: 98/238 - (41%)
• Gaps: 44/238 - (18%)

  Fly     7 IVNFILYIVNIVFLIVGILLIVLGSIMLSDLSRFDVAGSGTDPNTIPICVTVLGGLIFVVSFFGC 71
            ::.::|:..|::|.|.|..::..|..:|.. :.|.|........|:.....::|.:|.||:|.||
Human     8 LLKYVLFFFNLLFWICGCCILGFGIYLLIH-NNFGVLFHNLPSLTLGNVFVIVGSIIMVVAFLGC 71

  Fly    72 YGIFRQSVCMTGAYTSMVFVLFILQLVLTCWVFV-----NRSAFLG--------DMSNLVNLLWD 123
            .|..:::.|:..::..::.::.:.::.|...:||     |.....|        ...|.....||
Human    72 MGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAAWD 136

  Fly   124 SHDYTAMGVLEETFGCCGDTSYTNYNNIGLSVPGTCCGYLDRQATCNTPSVYQSRPGCSAKFEEF 188
            |        ::....|||....:::.:   ..|.:|..  ||:.           .||.||...:
Human   137 S--------IQSFLQCCGINGTSDWTS---GPPASCPS--DRKV-----------EGCYAKARLW 177

  Fly   189 WNDNMDIIRWSGLGLCIFDLVVFLIAGALT-NCM---RSQNAG 227
            ::.|...|  ..:.:|:..:.|..::.||| ||.   .||..|
Human   178 FHSNFLYI--GIITICVCVIEVLGMSFALTLNCQIDKTSQTIG 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ec	NP_523629.1	Tetraspanin	8..219	CDD:459767	46/224 (21%)
		tetraspanin_LEL	<137..192	CDD:351888	11/54 (20%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	46/225 (20%)
		CD53_like_LEL	104..186	CDD:239417	21/107 (20%)