Protein Alignment Tsp42Ec and Tspan6

DIOPT Version :10

• Sequence 1: NP_523629.1
• Gene: Tsp42Ec / 35612
• FlyBaseID: FBgn0033124
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_062630.2
• Gene: Tspan6 / 56496
• MGIID: 1926264
• Length: 245
• Species: Mus musculus
• Alignment Length: 240
• Identity: 61/240 - (25%)
• Similarity: 101/240 - (42%)
• Gaps: 39/240 - (16%)

  Fly     3 CLSGIV---NFILYIVNIVFLIVGILLIVLGSIMLSDLSRFDVAGSGTDPNTIPICVTVLGGLIF 64
            ||..::   .||.:|..::.|.|||    .|.:.|.:.  |.:...  ....:|..:...|.:|.
Mouse    16 CLKSVLLIYTFIFWITGVILLAVGI----WGKVSLENY--FSLLNE--KATNVPFVLIGTGTVII 72

  Fly    65 VVSFFGCYGIFRQSVCMTGAYTSMVFVLFILQLVLTCWVFVNR----SAFLGDMSNLVNLLWDSH 125
            ::..|||:...|.|..|...|...:.::|:::||.....||.|    ::|..:..|.:.....:.
Mouse    73 LLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTG 137

  Fly   126 DYTAMGV--LEETFGCCGDTSY-----TN-YNNIGLSVPGTCCG----YLDRQATCNTPSVYQSR 178
            ||.:..|  ::.|..|||.|:|     || |:..|.  |.:||.    |..|.|.      ..:.
Mouse   138 DYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSETGF--PKSCCKLEGCYPQRDAD------KVNE 194

  Fly   179 PGCSAKFEEFWNDNMDIIRWSGLGLCIFDLV-VFL---IAGALTN 219
            .||..|........|.::.....|:..|.|: :||   ::.|:||
Mouse   195 EGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ec	NP_523629.1	Tetraspanin	8..219	CDD:459767	57/233 (24%)
		tetraspanin_LEL	<137..192	CDD:351888	18/64 (28%)
Tspan6	NP_062630.2	Tetraspanin	17..235	CDD:459767	57/233 (24%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	27/104 (26%)