DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ec and Cd63

DIOPT Version :9

Sequence 1:NP_523629.1 Gene:Tsp42Ec / 35612 FlyBaseID:FBgn0033124 Length:232 Species:Drosophila melanogaster
Sequence 2:NP_001036045.1 Gene:Cd63 / 12512 MGIID:99529 Length:238 Species:Mus musculus


Alignment Length:243 Identity:52/243 - (21%)
Similarity:113/243 - (46%) Gaps:36/243 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGCLSGIVNFILYIVNIVFLIVGILLIVLG----SIMLSDLSRFDVAGSGTDPNTIPICVTVLGG 61
            |.|    |.|:||::.:.|....:.||.:|    .::...::....|||     .:|:.:..:|.
Mouse     7 MKC----VKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHETTAGS-----LLPVVIIAVGA 62

  Fly    62 LIFVVSFFGCYGIFRQSVCMTGAYTSMVFVLFILQLVLTCWVFVNRSAFLGDMS-----NLVNLL 121
            .:|:|:|.||.|..:::.|:...:...:.::.::::.:....:|.|.....:.:     .:.|.|
Mouse    63 FLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYL 127

  Fly   122 WDSHDYTAMGVLEETFGCCGDTSYTNYNNI-GLS---VPGTC-------CGYLDRQATCNTPSVY 175
            .|:...|.:..|::...|||.::||::.|| |::   ||.:|       ||...:::|.:|    
Mouse   128 KDNKTATILDKLQKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFKESTIHT---- 188

  Fly   176 QSRPGCSAKFEEFWNDNMDIIRWSGLGLCIFDLVVFLIAGALTNCMRS 223
               .||......:...|:.::..:.||:...:::..:.:..|...:||
Mouse   189 ---QGCVETIAIWLRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRS 233

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EcNP_523629.1 Tetraspannin 7..221 CDD:278750 48/233 (21%)
tetraspanin_LEL 104..193 CDD:239401 24/104 (23%)
Cd63NP_001036045.1 Tetraspannin 10..227 CDD:395265 47/228 (21%)
CD63_LEL 105..203 CDD:239419 24/104 (23%)
Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449 234..238 52/243 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3882
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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