Protein Alignment CG17002 and GPS2

DIOPT Version :9

• Sequence 1: NP_610253.1
• Gene: CG17002 / 35610
• FlyBaseID: FBgn0033122
• Length: 421
• Species: Drosophila melanogaster
• Sequence 2: NP_004480.1
• Gene: GPS2 / 2874
• HGNCID: 4550
• Length: 327
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 103/424 - (24%)
• Similarity: 161/424 - (37%)
• Gaps: 146/424 - (34%)

  Fly    10 SNAAAQAAKAERAEKLRGALKGFIVADRQR-RQEE------FEAQCEEQRLRREREEVERQNQVA 67
            |||.|:            ||...|:.:|:| ||||      .|.:.:|::.||:::|:|  .:::
Human    11 SNAMAR------------ALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEME--ERMS 61

  Fly    68 LDDTRGQITRLDEQLADLHSQKHQLTVQLKKVLNEDETRKKLAKENELFAIQQAAASSPVFLPPL 132
            |::|:.||.:|:|:|..|..:||||.:||||||:|:|.|:: .::::|..:..||....:.:
Human    62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRR-KEQSDLTTLTSAAYQQSLTV--- 122

  Fly   133 RLQHQHHTLMQKLPSGGQPGKRGRSPSPPSQQQA-------------YYKSAASYA-QQKHDDYR 183
                  ||....|...|.||...|..:..:..:|             |..|||::| ..:|
Human   123 ------HTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEH---- 177

  Fly   184 RAADYARLSWNKTAAQYPGTGTVFYQTVAPPPTTQHQADARLQSIYNYNLPLRQAYHVDLPSATV 248
                          .|:.|:....|.|..|||              :|. |.:.||.   ||..:
Human   178 --------------GQFQGSPGGAYGTAQPPP--------------HYG-PTQPAYS---PSQQL 210

  Fly   249 SKPPDSQSPKAPSQSQPMQVLHINLDQPTISQADLVAQAGGSLSVKASQPHVTMEK-LPDRYHIE 312
            ..|....:.:..||.||.........|||  |...: |.||:||::....|...:. ..|...:.
Human   211 RAPSAFPAVQYLSQPQPQPYAVHGHFQPT--QTGFL-QPGGALSLQKQMEHANQQTGFSDSSSLR 272

  Fly   313 VKHDGQPPSHVPPPPHLLPEGVIFKPLLNELSLHSNVLQISSSQFPPQNPKTAGSITQGYAPGRG 377
            ..|    |..:.|.|.||                      :|.|.|.|.
Human   273 PMH----PQALHPAPGLL----------------------ASPQLPVQM---------------- 295

  Fly   378 GSAHEQQLARQQLAMLPGQPGAPSG-SGSAQPPP 410
                              ||...|| :.::||.|
Human   296 ------------------QPAGKSGFAATSQPGP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17002	NP_610253.1	G_path_suppress	23..271	CDD:292610	71/268 (26%)
GPS2	NP_004480.1	G_path_suppress	5..292	CDD:406402	94/369 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..65		13/40 (33%)
		interaction with SUMO. /evidence=ECO:0000269|PubMed:20159957	61..94		16/32 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..208		13/66 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..327		19/119 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141963
Domainoid	1	1.000	72	1.000	Domainoid score	I9372
eggNOG	1	0.900	-	-		E1_298IM
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	78	1.000	Inparanoid score	I5252
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22654
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5091
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.920