DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vimar and ARIA

DIOPT Version :9

Sequence 1:	NP_995767.1	Gene:	vimar / 35609	FlyBaseID:	FBgn0022960	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_850852.1	Gene:	ARIA / 832053	AraportID:	AT5G19330	Length:	710	Species:	Arabidopsis thaliana

Alignment Length:	750	Identity:	146/750 - (19%)
Similarity:	249/750 - (33%)	Gaps:	274/750 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IEKLKTTSVSPANTTNLLCEISATKD--PKLFDKHELAECFLGLTKCDDTNVRKEAAKCIAEITK 72
            :|..:.::||......||.|::|...  ...|...|           .|....|.|.:.:||:.|
plant    30 VEDREISAVSTDGGQALLSEVAAQVSVLNSAFSWQE-----------SDRAAAKRATQVLAELAK 83

  Fly    73 SEVQRKKFTKRNIIAAFLECLRQVPTSDGSM-ELPIQICRALGNICYLNDEARDLILELE-GDAV 135
            :|...........:.|.:..|:..|.:||.: |.|.:                   .|:| |.|.
plant    84 NEDLVNVIVDGGAVPALMTHLQAPPYNDGDLAEKPYE-------------------HEVEKGSAF 129

  Fly   136 LLRLLDITTIEDVANAAQFIKVRGGLLSNYLLGGEGLAKRAMELGVMKKLQGIIDIGASNVEQHE 200
            .|.||.|        ..::.|:                              |:|.||
plant   130 ALGLLAI--------KPEYQKL------------------------------IVDKGA------- 149

  Fly   201 DLLLNTLPLLSILTENVSDLNFDSSLNIQLSRILAASTNPDLAEMCLELLHYQAESDEVKLILAK 265
                  ||.|..|.:...|.:...::|..:.|...|.||         |.|   |:..:|..:..
plant   150 ------LPHLVNLLKRNKDGSSSRAVNSVIRRAADAITN---------LAH---ENSSIKTRVRV 196

  Fly   266 DGLCETIYNLLEKYKTLASTSEARALMKLA------------CE----LIVLILTGDDSMHY--- 311
            :|....:..|||...:....:.|.||..||            |.    ||:::.:.|.::||
plant   197 EGGIPPLVELLEFSDSKVQRAAAGALRTLAFKNDDNKNQIVECNALPTLILMLGSEDAAIHYEAV 261

  Fly   312 ------LYTTPLLKNMVDWLDSTDIDLLTTG--------------------VLALGNFARTDSHC 350
                  ::::|.:|.          ::||.|                    .|.||.||.|||.|
plant   262 GVIGNLVHSSPHIKK----------EVLTAGALQPVIGLLSSCCPESQREAALLLGQFASTDSDC 316

  Fly   351 -IYFVEQQTMNKLLEVLAKNNGVKDDVRLQHALLSALRNLVIPKPNKNAVIQAGLVQTILPMLEI 414
             ::.|::..:..|:|:|.     ..||:|:.....||..|.....|:..:..:|.:..:|.:|:.
plant   317 KVHIVQRGAVRPLIEMLQ-----SPDVQLKEMSAFALGRLAQDAHNQAGIAHSGGLGPLLKLLDS 376

  Fly   415 H----QPPVVFKLLGTLR--------MTVDGQEKL--------ALELLKNKTL--IEQLVHWSKS 457
            .    |....|.|.|...        :.|.|.:||        |.:...:|||  :|:.:|
plant   377 RNGSLQHNAAFALYGLADNEDNVSDFIRVGGIQKLQDGEFIVQATKDCVSKTLKRLEEKIH---- 437

  Fly   458 SDYAGVTGESLRLMAWLIKHAYLS---KIAYALPR------------------------------ 489
                   |..||.:.:|::.:..|   ::|.||..
plant   438 -------GRVLRHLLYLMRISEKSIQRRVALALAHLCSPEDQRTIFIDDNGLELLLGLLGSLNTK 495

  Fly   490 ---KGDAPAEQIADKIPLTQDYD--------RSSLSEFLANEGTVEAMVSMLTAQHLVMQNEALI 543
               .|.|...::|:|.......|        |..|.|...|..|:..:..::..:......
plant   496 QQLDGAAALYKLANKSMALSPVDAAPPSPTQRVYLGEQYVNNATLSDVTFLVEGRTFYAHR---- 556

  Fly   544 ALCILSVVYLSQPSEAAQAQL-----------LQDELVKCEVGKKLAELISKSSDTMTKEIVENL 597
             :|:|:      .|:|.:|..           ::...:|.||.:.:...|...|..:|.||.:
plant   557 -ICLLA------SSDAFRAMFDGGYREKDARDIEIPNIKWEVFELMMRFIYTGSVDITNEISK-- 612

  Fly   598 QNCVNLLKSSEQLVAHLEQHNINELLKSIPILTEY 632
                :||::::|.           ||:.:..|.||
plant   613 ----DLLRAADQY-----------LLEGLKRLCEY 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vimar	NP_995767.1	ARM	55..155	CDD:237987	22/101 (22%)
		armadillo repeat	77..118	CDD:293788	7/41 (17%)
		armadillo repeat	124..165	CDD:293788	9/41 (22%)
		armadillo repeat	318..343	CDD:293788	7/44 (16%)
		ARM	322..428	CDD:237987	30/130 (23%)
		armadillo repeat	351..391	CDD:293788	10/39 (26%)
		armadillo repeat	396..428	CDD:293788	7/35 (20%)
ARIA	NP_850852.1	PLN03200	121..>353	CDD:215629	66/309 (21%)
		armadillo repeat	144..183	CDD:293788	14/60 (23%)
		armadillo repeat	194..225	CDD:293788	7/30 (23%)
		armadillo repeat	233..269	CDD:293788	6/35 (17%)
		armadillo repeat	275..306	CDD:293788	5/40 (13%)
		HEAT	283..>469	CDD:224331	45/201 (22%)
		armadillo repeat	317..351	CDD:293788	9/38 (24%)
		BTB_POZ_ARIA_plant	528..643	CDD:349661	24/132 (18%)
		BACK_ARIA_like	637..700	CDD:350579
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910