DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment vimar and ABAP1

DIOPT Version :9

Sequence 1:	NP_995767.1	Gene:	vimar / 35609	FlyBaseID:	FBgn0022960	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_196810.5	Gene:	ABAP1 / 831145	AraportID:	AT5G13060	Length:	737	Species:	Arabidopsis thaliana

Alignment Length:	707	Identity:	142/707 - (20%)
Similarity:	244/707 - (34%)	Gaps:	203/707 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SATKDPKLFDKHELAECFLGLTKCDDTNVRKEAAKCIAEITKSEVQRKKFTKRNIIAAFLECLRQ 95
            |:..||. || ||..               ||||..||::.|.:...:...:...|.|.:..|
plant    86 SSFSDPD-FD-HEAV---------------KEAAADIADLAKIDENVEIIVENGAIPALVRYL-- 131

  Fly    96 VPTSDGSMELPIQIC----------------RALGNICYLNDEARDLILE--------------- 129
                    |.|:.:|                .|||.|..:....:.||::
plant   132 --------ESPLVVCGNVPKSCEHKLEKDCALALGLIAAIQPGYQQLIVDAGAIVPTVKLLKRRG 188

  Fly   130 -----LEGDAVLLRLLDITT--IEDVANAAQFIKVRGGL-----LSNYLLGGEGLAKRAMELGVM 182
                 :..:||:.|..||.|  ..|.......|:|.||:     |.|:           .::.|.
plant   189 ECGECMFANAVIRRAADIITNIAHDNPRIKTNIRVEGGIAPLVELLNF-----------PDVKVQ 242

  Fly   183 KKLQGII-DIGASNVEQHEDLL-LNTLPLLSILTENVSDLNFDSSLNIQLSRILAASTNPDLAEM 245
            :...|.: .:...|.|....:: ||.||.|.::.::.     ||:::   ...:.|..|
plant   243 RAAAGALRTVSFRNDENKSQIVELNALPTLVLMLQSQ-----DSTVH---GEAIGAIGN------ 293

  Fly   246 CLELLHYQAESDEVKLILAKDGLCETIYNLLEKYKTLASTSEARALM--KLACELIVLILTGDDS 308
               |:|   .|.::|..:.:.|..:.:..||.  .|...|....||:  :.|..      ..|..
plant   294 ---LVH---SSPDIKKEVIRAGALQPVIGLLS--STCLETQREAALLIGQFAAP------DSDCK 344

  Fly   309 MHYLY---TTPLLKNMVDWLDSTDIDLLTTGVLALGNFARTDSHCIYFVEQQTMNKLLEVLAKNN 370
            :|...   .|||:|    .|:|:|..::.....|||..|:...:......:..:..||.:|....
plant   345 VHIAQRGAITPLIK----MLESSDEQVVEMSAFALGRLAQDAHNQAGIAHRGGIISLLNLLDVKT 405

  Fly   371 GVKDDVRLQHALLSALRNLVIPKPNKNAVIQAGLVQ-------TILPMLE------------IHQ 416
            |     .:||....||..|...:.|....|:||.:|       |:.|..:            ||.
plant   406 G-----SVQHNAAFALYGLADNEENVADFIKAGGIQKLQDDNFTVQPTRDCVVRTLKRLQNKIHG 465

  Fly   417 PPV--VFKLLGTLRMTVDGQEKLALELL---KNKTLI----------EQLVHWSKSSDYAGVTGE 466
            |.:  :..|:.|...||..:..|||..|   |:..||          .:|:::|.:.
plant   466 PVLNQLLYLMRTAEKTVQIRIALALAHLCDPKDGKLIFIDNNGVEFLLELLYFSSNK-------- 522

  Fly   467 SLRLMAWLIKHAYLSKIAYALPRKGDAPA-EQIADKIPLTQDYDRSSLSEFLANEGTVEAMVSML 530
                     :..|.|...|.|.:|..:.| |..|...|..|.:    |.|...|..|:..:..::
plant   523 ---------QQRYSSSALYELAKKATSFAPEDSAPCSPTQQVF----LGEKFVNNPTMSDVTFLI 574

  Fly   531 TAQHLVMQNEALIALCILSVVYLSQPSEAAQAQLLQDELVKCEVGKKLAELISKSSDTMTKEIVE 595
            ..:........|:|...:.........:...||.::...::.||.:.:.:.|......:.|.:.:
plant   575 DGKQFYAHKIGLVASSDIFRAMFDGLYKERNAQNVEIPNIRWEVFELMMKFIYSGRINIAKHLAK 639

  Fly   596 NLQNCVNLLKSSEQLVAHLEQH------------NINELLK-----SIPILTEYCTL 635
            :|     |:.:.:.|:..|::.            ||.|:.:     :...|...|||
plant   640 DL-----LVAADQYLLEGLKRQCEYTIAQEICLDNIPEMYELADTFNASALRRACTL 691

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vimar	NP_995767.1	ARM	55..155	CDD:237987	26/137 (19%)
		armadillo repeat	77..118	CDD:293788	10/56 (18%)
		armadillo repeat	124..165	CDD:293788	14/67 (21%)
		armadillo repeat	318..343	CDD:293788	7/24 (29%)
		ARM	322..428	CDD:237987	28/126 (22%)
		armadillo repeat	351..391	CDD:293788	9/39 (23%)
		armadillo repeat	396..428	CDD:293788	11/52 (21%)
ABAP1	NP_196810.5	SRP1	17..440	CDD:227396	91/428 (21%)
		armadillo repeat	117..160	CDD:293788	9/52 (17%)
		armadillo repeat	221..252	CDD:293788	8/41 (20%)
		armadillo repeat	260..296	CDD:293788	10/52 (19%)
		armadillo repeat	302..333	CDD:293788	8/32 (25%)
		armadillo repeat	344..378	CDD:293788	11/37 (30%)
		armadillo repeat	385..416	CDD:293788	6/35 (17%)
		HEAT repeat	423..459	CDD:293787	7/35 (20%)
		armadillo repeat	500..534	CDD:293788	7/50 (14%)
		BTB_POZ_ARIA_plant	555..670	CDD:349661	16/123 (13%)
		BACK	664..727	CDD:421692	7/28 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910