DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment vimar and si:dkey-21e13.3

DIOPT Version :9

Sequence 1:	NP_995767.1	Gene:	vimar / 35609	FlyBaseID:	FBgn0022960	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	NP_001314946.1	Gene:	si:dkey-21e13.3 / 100150043	ZFINID:	ZDB-GENE-130531-75	Length:	291	Species:	Danio rerio

Alignment Length:	280	Identity:	67/280 - (23%)
Similarity:	104/280 - (37%)	Gaps:	70/280 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 PKPNKNAVIQAGLVQTILPMLEIHQPPVVFKLLGTLRMTVDGQEKLALELLKNKTLIEQLVHWSK 456
            ||.:.:|.|:|..|.|.|...|             |:..:|....:|:|  :...:.||:|
Zfish    14 PKDSLSAAIEAISVSTELVEDE-------------LKPYLDAVLNVAIE--RKNGISEQVV---- 59

  Fly   457 SSDYAGVTGESLRLMAWLIKHAYLSKIAYALPRKGDAPA-EQIAD--------KIPLTQD----- 507
            .|....|..:.||..:.|..|.  :::...|.|  |||. :|..|        .:.|:||
Zfish    60 ESGILPVLAQILRRKSTLTTHT--ARLVAELAR--DAPVRDQCFDTGIVSALVTLLLSQDQDLLL 120

  Fly   508 ----------YDRSSLSEFLANEGTVEAMVSMLTAQHLVMQNEALIALCILSVVYLSQPSEAAQA 562
                      ||.:...|.....|.|..:||:| .||  ..||||.:.|:|::..|:...|...:
Zfish   121 HVSQAIARICYDSNLQQERFLRLGAVPRLVSVL-LQH--SNNEALRSSCLLALCNLADMGEEDGS 182

  Fly   563 QLLQDELVKCEVGKKLAELISKSSDTMTKEI----------------VENLQNCVNLLKSSEQLV 611
            .|..:|......|:.:....|:.|...:..:                ||.||.|..:|..:..
Zfish   183 MLSWEEGAHFGEGEHVFRGTSRYSFGFSSAVTVVRLKQWTNGQYSVAVEVLQRCSTMLWGANN-- 245

  Fly   612 AHLEQHNINEL--LKSIPIL 629
            .|...|.::..  |.|.|.|
Zfish   246 GHQNGHRLSNFSNLSSCPKL 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
vimar	NP_995767.1	ARM	55..155	CDD:237987
		armadillo repeat	77..118	CDD:293788
		armadillo repeat	124..165	CDD:293788
		armadillo repeat	318..343	CDD:293788
		ARM	322..428	CDD:237987	9/35 (26%)
		armadillo repeat	351..391	CDD:293788
		armadillo repeat	396..428	CDD:293788	7/31 (23%)
si:dkey-21e13.3	NP_001314946.1	ARM	56..174	CDD:237987	35/128 (27%)
		armadillo repeat	57..88	CDD:293788	8/36 (22%)
		armadillo repeat	95..131	CDD:293788	5/35 (14%)
		armadillo repeat	137..173	CDD:293788	14/38 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004617
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910