Protein Alignment Cyp6u1 and ERG11

DIOPT Version :9

• Sequence 1: NP_001286149.1
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_011871.1
• Gene: ERG11 / 856398
• SGDID: S000001049
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 111/496 - (22%)
• Similarity: 200/496 - (40%)
• Gaps: 90/496 - (18%)

  Fly    61 QDIYTAYKGRAPFVGFYAC----------LKPFILALDLKLVHQIIFTDAGHFTSRG----LYSN 111
            |.:|:..|.|.|.| ||..          :||:....:.:..:..||:    |...|    :|..
Yeast    46 QLLYSLRKDRPPLV-FYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFS----FVLLGRVMTVYLG 105

  Fly   112 PSGEPLSHNLLQLDGHKWRSLHAKSAEVFTPANMQKLLV-----RLSQISSRIQRDLGEKSLQTI 171
            |.|.....|....|    .|..|..|.:.||...:.::.     ||.:....::..|.:::.::.
Yeast   106 PKGHEFVFNAKLAD----VSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSY 166

  Fly   172 --NISELVGAY---------------NTDVMASM--------AFGLVGQD-----NVEFAKWTRN 206
              .|:|.|..|               ..|||.:.        :..|:|::     :.:||    .
Yeast   167 VPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFA----Y 227

  Fly   207 YWADFRMWQAYLALEFPLIARLLQYKSYAEPATAYFQKVALSQLQLHRR----RDRQPLQTFLQ- 266
            .::|.......:...||.:.  |::....:.|........:|.::..|:    :||..:.:.::
Yeast   228 LYSDLDKGFTPINFVFPNLP--LEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDRDLIDSLMKN 290

  Fly   267 -LYSNAEKPLTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQ 330
             .|.:..| :||.|||....|.::.|.....||.|:.|..||.:|:||.....|..:.|:....:
Yeast   291 STYKDGVK-MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKE 354

  Fly   331 VTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGI 395
            :|.:.|:|:....|.:.||||:|.|...|.|:..|:..||.:.:||..|.:||:.....|:....
Yeast   355 LTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEY 419

  Fly   396 YENPQRFYPERFEEQARRSRP----------------AAAFLPFGDGLRGCIAARFAEQQLLVGL 444
            :.|..:|...|:.:.:..|..                ::.:||||.|...||...||..||.|.:
Yeast   420 FPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLM 484

  Fly   445 VALLRQHR-YAPSAETSIPVEYDNRRLLLMPKSDIKLSVER 484
            ...:|..: :.|..:|..|.::.:  ::.:|....|:..|:
Yeast   485 SIFIRTLKWHYPEGKTVPPPDFTS--MVTLPTGPAKIIWEK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	108/485 (22%)
ERG11	NP_011871.1	CYP51-like	83..521	CDD:410668	100/454 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I1492
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1477
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050