DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6u1 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_001286149.1	Gene:	Cyp6u1 / 35608	FlyBaseID:	FBgn0033121	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	116/570 - (20%)
Similarity:	210/570 - (36%)	Gaps:	137/570 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MHRTLLTALGALSVVYALVKFSLGY----------WKRR------GILHEKPKFLWGNIKGVVSG 52
            |...::..:.|:..:..:..||:||          |:.|      |:....|....||:..:...
plant     1 MESLVVHTVNAIWCIVIVGIFSVGYHVYGRAVVEQWRMRRSLKLQGVKGPPPSIFNGNVSEMQRI 65

  Fly    53 KRHAQDALQD------------------------IYTAYKGRAPFVGFYACLKPFILALDLKLVH 93
            :..|:....|                        |||...|          ||..:.....::|.
plant    66 QSEAKHCSGDNIISHDYSSSLFPHFDHWRKQYGRIYTYSTG----------LKQHLYINHPEMVK 120

  Fly    94 QIIFTDA------GHFTSRGLYSNPSGEPLSHNLLQLDGHKWRSLHAKSAEVFTP---ANMQKLL 149
            ::..|:.      .|.|.|   .||.   |.:.::..:|..|.......|..||.   ..|..|:
plant   121 ELSQTNTLNLGRITHITKR---LNPI---LGNGIITSNGPHWAHQRRIIAYEFTHDKIKGMVGLM 179

  Fly   150 VR-----LSQISSRIQRDLGEKSLQTINISELVGAYNTDVMASMAFGLVGQDNVEFAKWTRNYWA 209
            |.     |::....::|. ||.... |.:.|.:...:.||:|...||                 :
plant   180 VESAMPMLNKWEEMVKRG-GEMGCD-IRVDEDLKDVSADVIAKACFG-----------------S 225

  Fly   210 DFRMWQAYLALEFPLIAR------LLQYKSYA-------------------EPATAYFQKVALSQ 249
            .|...:|..::...|:..      |.::..:.                   |..::.::.|...:
plant   226 SFSKGKAIFSMIRDLLTAITKRSVLFRFNGFTDMVFGSKKHGDVDIDALEMELESSIWETVKERE 290

  Fly   250 LQLHRRRDRQPLQTFLQ-LYSNAEKPLTDIE-----IAGQAFGFVLAGLGPLNATLAFCLYELAR 308
            ::......:..:|..|: ...:.:..|.|..     :.........||......::::||..||.
plant   291 IECKDTHKKDLMQLILEGAMRSCDGNLWDKSAYRRFVVDNCKSIYFAGHDSTAVSVSWCLMLLAL 355

  Fly   309 QPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFEVPGSV 373
            .|..|.:.|.||..:.:  .|....|.:..|:....|:.||:||:.|.|.:.|.|:|:..: |.:
plant   356 NPSWQVKIRDEILSSCK--NGIPDAESIPNLKTVTMVIQETMRLYPPAPIVGREASKDIRL-GDL 417

  Fly   374 FVIAKGNNV--LIPTAAIHMDPGIY-ENPQRFYPERFEEQ-ARRSRPAAAFLPFGDGLRGCIAAR 434
             |:.||..:  |||  |:|.||.|: .:...|.||||.|. ::..:...:::|||.|.|.|:...
plant   418 -VVPKGVCIWTLIP--ALHRDPEIWGPDANDFKPERFSEGISKACKYPQSYIPFGLGPRTCVGKN 479

  Fly   435 FA--EQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSV 482
            |.  |.::||.|:........:|:.:.|     .:.:||:.|:..:.:.|
plant   480 FGMMEVKVLVSLIVSKFSFTLSPTYQHS-----PSHKLLVEPQHGVVIRV 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	105/511 (21%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	108/532 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000