DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6u1 and CYP705A8

DIOPT Version :9

Sequence 1:	NP_001286149.1	Gene:	Cyp6u1 / 35608	FlyBaseID:	FBgn0033121	Length:	488	Species:	Drosophila melanogaster
Sequence 2:	NP_180268.1	Gene:	CYP705A8 / 817242	AraportID:	AT2G27000	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	109/523 - (20%)
Similarity:	198/523 - (37%)	Gaps:	121/523 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLMHRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKF------------LWGNIKGVVSGK 53
            :|.::..:|..|..||:        |.|    ....:|||.            :.|::..::|..
plant     7 VDFVNCLILILLCLLSI--------LCY----SFFFKKPKDGFNLPPSPPSLPIIGHLHHLLSLF 59

  Fly    54 RHAQDALQDIYTAYKGRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPL- 117
            .|.  :||.:.:.|   .|.:..:....|.:|.....:.::|......:.::|...:|.....|
plant    60 MHR--SLQKLSSKY---GPLLYLHVFNVPILLVSSPSIAYEIFRAQDVNVSTRDFPTNEGSLFLG 119

  Fly   118 SHNLLQLD-GHKWRSLHAKSAEVFTPANMQKLLV---------------RLSQISSRIQRDLGEK 166
            |.:.:... |..|:.             |:||:|               |.::: .|...:|.:|
plant   120 SFSFITAPYGEYWKF-------------MKKLIVTKLLGPQALERSQRIRANEV-ERFYSNLLDK 170

  Fly   167 SL--QTINISELVGAYNTDVMASMAFG-LVGQDNVEFAKWTRNYWADFRMWQAYLALEFPLIARL 228
            ::  :::.|::.......:::..|..| ...::|.| |:..|..     :.::...|:..|:|.:
plant   171 AMKKESVEIADEAMKLVNNIICKMIMGRTCSEENGE-AERIRGL-----VTKSDALLKKFLLAAI 229

  Fly   229 LQYKSYAEPATAYFQKV----------ALSQLQL---HRRRDRQP----LQTFLQLYSN--AEKP 274
            |: |...:.....|:||          .|.::.:   .|..:.|.    :...|::|.:  :|..
plant   230 LR-KPLKKIGITLFKKVFMDISLKFDEVLEKILVENEERLEENQQGTDIMDKLLEVYGDKTSEYK 293

  Fly   275 LTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQ---VTPECL 336
            :|...|.........||......|:.:.:.|:.....:.:|.|.||:..:    |:   :....|
plant   294 ITRDHIKSLFVDLFFAGTDTATHTIEWTMAEIMNNSLILERLREEIDSVV----GKTRLIQETDL 354

  Fly   337 RELRYTKQVLNETLRLHTPHPFLLRRATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQR 401
            ..|.|.:..:.|.||||...|.:||.......:.|  |.|.|...:::...||..||..:|:|..
plant   355 PNLLYLQATVKEGLRLHPTIPLVLRTFQDGCTIGG--FSIPKKTKLVVNGYAIMRDPDNWEDPLE 417

  Fly   402 FYPERFEEQARRSRPAA------AFLPFGDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETS 460
            |.||||...:|.|:..|      .:|.||.|.|||.....|                |. |.||:
plant   418 FKPERFLASSRSSQKDAIKEEVLKYLSFGSGRRGCPGVNLA----------------YV-SVETA 465

  Fly   461 IPV 463
            |.|
plant   466 IGV 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	102/486 (21%)
CYP705A8	NP_180268.1	p450	55..506	CDD:299894	98/463 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010