Protein Alignment Cyp6u1 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_610252.3
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 514
• Identity: 137/514 - (26%)
• Similarity: 244/514 - (47%)
• Gaps: 49/514 - (9%)

  Fly     2 DLMHRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDIYTA 66
            :|..:|.:..:.:|...|....:|.|.:|:.||...||..|:|||...:.|.....|   |.|..
Mouse     6 NLSIQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYLDGMWKFDD---DCYKK 67

  Fly    67 YKGRAPFVGFYACLKPFILALDLKLVHQIIFTDA-GHFTSRGLYSNPSGEPLSHNLLQLDGHKWR 130
            |   ....|||...:|.:..:|.:::..::..:. ..||:|..: .|.|. |..::...:..:|:
Mouse    68 Y---GKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPF-GPVGF-LKKSITISEDEEWK 127

  Fly   131 SLHAKSAEVFTPANMQKLLVRLSQISSRIQRDL--GEKSLQTINISELVGAYNTDVMASMAFGLV 193
            .|....:..||.:.::::...:.|....:.|:|  .|:..:.||:.::.|||:.||:...:.|:
Mouse   128 RLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGTSCGV- 191

  Fly   194 GQDNVEFAKWTRNYWAD-------FRMWQAYL--ALEFPL---IARLLQYKSYAEPATAYFQKVA 246
               |::.....::.:..       |:.:..:|  .:.||.   |..:|....:...:..:|:|..
Mouse   192 ---NIDSLNNPQDPFVQKIKKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIFPRQSMNFFKKFV 253

  Fly   247 LSQLQLHRRRDRQPLQ-----TFLQLYSNAE--------KPLTDIEIAGQAFGFVLAGLGPLNAT 298
            ...     ::||....     .||||..|.:        |.|:|:|:|.|...|:..|....:.:
Mouse   254 KKM-----KKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGGYDGTSTS 313

  Fly   299 LAFCLYELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRA 363
            ::|.:||||..|:||.:.:.||::|| .:...||.:.|.::.|...|:||:|||:.....:.|.:
Mouse   314 ISFIMYELATHPDVQKKLQDEIDRAL-PNKAPVTYDALMDMEYLDMVVNESLRLYPVVSRIDRFS 377

  Fly   364 TKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGLR 428
            .|:.|:.| || |.||..|:||...:|.||..:..|:.|.||||.::.:.:.....::|||:|.|
Mouse   378 KKDVEIHG-VF-IPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPYIYMPFGNGPR 440

  Fly   429 GCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDNRRLLLMPKSDIKLSVERVDK 487
            .||..|||...:.:.:..:|:.....|..||.|||:. :|:.:..|:..|.|.....||
Mouse   441 NCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKI-SRQPIFRPEKPIILKFVSRDK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_610252.3	CYP6-like	69..479	CDD:410679	113/437 (26%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	115/442 (26%)