Protein Alignment Cyp6u1 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_610252.3
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Alignment Length: 535
• Identity: 148/535 - (27%)
• Similarity: 240/535 - (44%)
• Gaps: 82/535 - (15%)

  Fly     7 TLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDIYTAYKGRA 71
            |||.||.||...|::..||  ..::.||.|.||....||:.....|...:|..|::.|      .
Mouse    19 TLLVALLALLKWYSMSAFS--RLEKLGIRHPKPSPFVGNLMFFRQGFWESQLELRERY------G 75

  Fly    72 PFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLLQLDGHKWRSLHAKS 136
            |..|:|...:..::..:..::.|::..:..:|::| :.|....:.::.::|.|...:|..:....
Mouse    76 PLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNR-MASGLEPKMVADSVLLLRDRRWEEVRGAL 139

  Fly   137 AEVFTPANMQKLLVRLSQISSRIQRDLGE--KSLQTINISELVGAYNTDVMASMAFG--LVGQDN 197
            ...|:|..:.::...:||....:...|..  .|....||......|..||:||:|||  :..|::
Mouse   140 MSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFGTQVDSQNS 204

  Fly   198 VE--FAKWTRNYWADFRMWQAYLA--LEFPLI----ARLLQYKSYAEPATAYFQK-----VALSQ 249
            .|  |.:..|.. :.|.:.:..|.  |.||.|    ||:|..|:..| ...:|..     :||..
Mouse   205 PEDPFVQHCRRA-STFCIPRPLLVLILSFPSIMVPLARILPNKNRDE-LNGFFNTLIRNVIALRD 267

  Fly   250 LQL--HRRRDRQPLQTFLQLYSNAE-------------------------------------KPL 275
            .|.  .||||      |||:..:|:                                     ||.
Mouse   268 QQAAEERRRD------FLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPTSTSKPF 326

  Fly   276 TDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEHGGQVTPE--CLRE 338
            |..||.||||.|::||...:..||:|..|.||..|:.|:|...|::..:.:|   ..||  .|:|
Mouse   327 TVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKH---PAPEYHSLQE 388

  Fly   339 -LRYTKQVLNETLRLHTPHPFLLRRATKEFEVPGSVFVIAKGNNVLIPTAAIHMDPGIYENPQRF 402
             |.|...|::||||::.|.....|.|.::.||.|.  .|..|..:.|...|:|.||..:.||:.|
Mouse   389 GLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQ--RIPAGTVLEIAVGALHHDPEHWPNPETF 451

  Fly   403 YPERFEEQARRSRPAAAFLPFGDGLRGCIAARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYDN 467
            .||||..:||..|....:||||.|.|.|:..|.....:.:.::.:|.:.|:..|.||.:|::.::
Mouse   452 DPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPLQLES 516

  Fly   468 RRLLLMPKSDIKLSV 482
            :. .|.||:.:.:.:
Mouse   517 KS-ALGPKNGVYIKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_610252.3	CYP6-like	69..479	CDD:410679	127/468 (27%)
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	128/473 (27%)