Protein Alignment Cyp6u1 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_610252.3
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 125/551 - (22%)
• Similarity: 222/551 - (40%)
• Gaps: 136/551 - (24%)

  Fly    16 SVVYALVKFSLGYWK---RRGIL----------------HEKPKFL--------WGNIKGVVSGK 53
            :|:..:..:|:..|.   |:||.                ||.|.||        :|.:.|...|.
 Worm     8 AVLLGVFTYSVWIWSYFIRKGIKGPRGFPGIGMLIQTIDHENPPFLKYRDWTKQYGPVYGFTEGP 72

  Fly    54 RHAQ-----DALQDIYTAYKGRAPFVGFYA-CLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNP 112
            :...     :.:.:|:     :..|..||. .|:|.|
 Worm    73 QQTMIISEPEMVNEIF-----KKQFDNFYGRKLRPII---------------------------- 104

  Fly   113 SGEPLSH---NLLQLDGHKWRSLHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEKSLQTINIS 174
             |:|...   |:....|.:|:.|...|:..|:..:::|:...:.:..:.|..::.:|..:..:|.
 Worm   105 -GDPEKDKRVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDID 168

  Fly   175 ELV--GAYNTDVMASMAFGLVGQDNVEFAKWTRNYWADFR-MWQAYLALE-FPLIARLLQYKSYA 235
            .|:  ..|...|::.:|.| ..:.|:..........|.|. .|..:|... ||.:|.:.:..|..
 Worm   169 MLIVYQEYTLGVISRIALG-QSESNMFKNPLLPKVQAIFNGSWHVFLITGIFPPLAGVFRKMSKM 232

  Fly   236 EPAT--AYFQKVALSQLQLHRRRDR------------QPLQTFLQLYSNAEKP------------ 274
            .||:  ..|:...|.::.:..|.|:            :| |.|:.|:.:|..|
 Worm   233 LPASFIPAFKIFDLIEVAVQARIDQRAKDEIKGVEPGEP-QDFIDLFLDARVPDVKILSGEANED 296

  Fly   275 ------------LTDIEIAGQAFGFVLAGLGPLNATLAFCLYELARQPEVQDRTRLEINKALEEH 327
                        ||..||..|.|.|:.||......:|::..|.||..||:|.:.:.|:::...:
 Worm   297 FAKSSVVKINKELTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDRECPD- 360

  Fly   328 GGQVTPEC----LRELRYTKQVLNETLRLH----TPHPFLLRRATKEFEVPGSVFVIAKGNNVLI 384
                 ||.    |.:|:|.:.|:.|||||:    |.:   .|:..:|..:.|..|  .:|.|:.:
 Worm   361 -----PEIFFDHLSKLKYLECVMKETLRLYPLGTTAN---TRKCMRETTINGVNF--DEGMNIQV 415

  Fly   385 PTAAIHMDPGIY-ENPQRFYPERFEEQA-RRSRPAAAFLPFGDGLRGCIAARFAEQQLLVGLVAL 447
            .|..:|.:|.|: |:.:.|.|||:|..| .......:::|||.|.|.||..|.|:.:..:.|..:
 Worm   416 DTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQI 480

  Fly   448 LRQHRYAPSAETSIPVEYDNRRLLLMPKSDI 478
            |:::.:..:..|.|||:... :|.|.|:|.|
 Worm   481 LKEYSFRTTKNTQIPVKLVG-KLTLSPESVI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6u1	NP_610252.3	CYP6-like	69..479	CDD:410679	110/466 (24%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	114/498 (23%)